Magnesium and strontium both play important roles in the growth of bone and so are desirable ions for substitution into hydroxyapatite (HA) intended for use as bioinstructive bone substitutes. A range of compositions were prepared by a solid state method based on the nominal composition of HA (Ca10(PO4)6(OH)2), with various levels of strontium and/or magnesium substitution: strontium-substituted HA (Ca8Sr2(PO4)6(OH)2), magnesium-substituted HA (Ca9.8Mg0.2(PO4)6(OH)2 and Ca9Mg(PO4)6(OH)2), and strontium and magnesium co-substituted HA (Ca7.8Sr2Mg0.2(PO4)6(OH)2 and Ca7Sr2Mg(PO4)6(OH)2). Materials were characterised by powder X-ray diffraction, Fourier-transform infrared spectroscopy and Raman spectroscopy. These analyses indicated that the co-substituted materials were composed of mixtures of strontium-substituted hydroxyapatite and magnesium and strontium co-substituted β-tricalcium phosphate. In the magnesium-substituted materials, increased magnesium content was related to increased proportion of β-tricalcium phosphate phase, both with and without strontium co-substitution. The unsubstituted and strontium mono-substituted materials, however, were pure apatite phase, suggesting that magnesium was the destabilising factor in the phase compositions of the magnesium mono-substituted and magnesium and strontium co-substituted materials

Synthesis and Characterisation of Strontium and Magnesium Co-Substituted Biphasic Calcium Phosphates / Flora E., Imrie; Valentina, Aina; Lusvardi, Gigliola; Malavasi, Gianluca; Iain R., Gibson; Giuseppina, Cerrato; Basil, Annaz. - ELETTRONICO. - 529-530:1(2013), pp. 88-93. [10.4028/www.scientific.net/KEM.529-530.88]

Synthesis and Characterisation of Strontium and Magnesium Co-Substituted Biphasic Calcium Phosphates

LUSVARDI, Gigliola;MALAVASI, Gianluca;
2013

Abstract

Magnesium and strontium both play important roles in the growth of bone and so are desirable ions for substitution into hydroxyapatite (HA) intended for use as bioinstructive bone substitutes. A range of compositions were prepared by a solid state method based on the nominal composition of HA (Ca10(PO4)6(OH)2), with various levels of strontium and/or magnesium substitution: strontium-substituted HA (Ca8Sr2(PO4)6(OH)2), magnesium-substituted HA (Ca9.8Mg0.2(PO4)6(OH)2 and Ca9Mg(PO4)6(OH)2), and strontium and magnesium co-substituted HA (Ca7.8Sr2Mg0.2(PO4)6(OH)2 and Ca7Sr2Mg(PO4)6(OH)2). Materials were characterised by powder X-ray diffraction, Fourier-transform infrared spectroscopy and Raman spectroscopy. These analyses indicated that the co-substituted materials were composed of mixtures of strontium-substituted hydroxyapatite and magnesium and strontium co-substituted β-tricalcium phosphate. In the magnesium-substituted materials, increased magnesium content was related to increased proportion of β-tricalcium phosphate phase, both with and without strontium co-substitution. The unsubstituted and strontium mono-substituted materials, however, were pure apatite phase, suggesting that magnesium was the destabilising factor in the phase compositions of the magnesium mono-substituted and magnesium and strontium co-substituted materials
2013
Key Engineering Materials Vol. 529-530 (Bioceramics 24)
9783037855171
Trans Tech Publications Ltd
Synthesis and Characterisation of Strontium and Magnesium Co-Substituted Biphasic Calcium Phosphates / Flora E., Imrie; Valentina, Aina; Lusvardi, Gigliola; Malavasi, Gianluca; Iain R., Gibson; Giuseppina, Cerrato; Basil, Annaz. - ELETTRONICO. - 529-530:1(2013), pp. 88-93. [10.4028/www.scientific.net/KEM.529-530.88]
Flora E., Imrie; Valentina, Aina; Lusvardi, Gigliola; Malavasi, Gianluca; Iain R., Gibson; Giuseppina, Cerrato; Basil, Annaz
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/790689
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