Epidemiology of NAFLD is not well defined. Estimated prevalence in teh general population is 20% for NAFLD and 2% for NASH. the disease affects all ages, males are more affected than females . Associated conditions are obeisty ,type 2 diabetes , hyperlypemia, all features of metabolic syndroem. Natural history includes a clinically nenign course for steatosis and teh progression of nASH to cirrhosis in a significant proportion of cases(20%) and eventually to hepatocellular carcinoma.. steatosis is a negative predictor for graft surbvival in orthotopic liver transplantation and is associated with the progression of hepatitis C virus to cirrhosis.
Epidemiologia e storia naturale dell'epatopatia steatosica non alcolica / Loria, Paola; Lonardo, A; Lombardini, S; Leonardi, F; Carulli, Lucia; Ganazzi, D; Rudilosso, A; Verrone, Am; Ricchi, M; Carulli, Nicola. - In: ANNALI ITALIANI DI MEDICINA INTERNA. SUPPLEMENTO. - ISSN 1122-0538. - STAMPA. - 18:(2003), pp. 12-28.
Epidemiologia e storia naturale dell'epatopatia steatosica non alcolica
LORIA, Paola;CARULLI, Lucia;CARULLI, Nicola
2003
Abstract
Epidemiology of NAFLD is not well defined. Estimated prevalence in teh general population is 20% for NAFLD and 2% for NASH. the disease affects all ages, males are more affected than females . Associated conditions are obeisty ,type 2 diabetes , hyperlypemia, all features of metabolic syndroem. Natural history includes a clinically nenign course for steatosis and teh progression of nASH to cirrhosis in a significant proportion of cases(20%) and eventually to hepatocellular carcinoma.. steatosis is a negative predictor for graft surbvival in orthotopic liver transplantation and is associated with the progression of hepatitis C virus to cirrhosis.
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