The breakpoints on chromosome 22 we analyzed by molecular hybridization in 22 cases os chronic myeloid leukemia. In 3 patients the breakpoint was not detectable inside the bcr region in spite of the presence of a cytogenetically evident t(9;22) translocation. The breakpoint location remained unchanged in the 4 patients studied during after progression
Molecular study of the Philadelphia translocation in chronic myelogenous leukemia in different stages of the disease / Torelli, Giuseppe; L., Selleri; Emilia, Giovanni; Narni, Franco; A., Colò; Zucchini, Patrizia; A., Donelli; D., Venturelli; Torelli, Umberto. - In: HAEMATOLOGICA. - ISSN 0390-6078. - STAMPA. - 72:(1987), pp. 201-208.
Molecular study of the Philadelphia translocation in chronic myelogenous leukemia in different stages of the disease.
TORELLI, Giuseppe;EMILIA, Giovanni;NARNI, Franco;ZUCCHINI, Patrizia;TORELLI, Umberto
1987
Abstract
The breakpoints on chromosome 22 we analyzed by molecular hybridization in 22 cases os chronic myeloid leukemia. In 3 patients the breakpoint was not detectable inside the bcr region in spite of the presence of a cytogenetically evident t(9;22) translocation. The breakpoint location remained unchanged in the 4 patients studied during after progression
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