Heterogeneous nuclear RNA was extracted from normal PHA-stimulated human lymphocytes and acute myeloid leukemia blast cells. Experiments were performed to determine the hybridization kinetics of these RNA's to human DNA. The best least squares solutions indicate in the hybridization reaction of both normal and leukemic RNA two main components. For leukemic cell RNA the rate constants of both components were significantly different from that of normal cell RNA. In particular, the difference between the rate constants of the second lower component suggests that the slowly hybridizing sequences in leukemic cell RNA have a degree of repetition higher than of the corresponding sequences of normal cell RNA.
Kinetics of hybridization to human DNA of heterogeneous nuclear RNA isolated from normal human lymphoblasts and acute leukemia blast cells / Torelli, Giuseppe; Narni, Franco; Franchini, G; Donelli, A; Ferrari, Sergio; Calabretta, Bruno; Torelli, Umberto; Bosi, Paolo. - In: MOLECULAR BIOLOGY REPORTS. - ISSN 0301-4851. - STAMPA. - 5(1979), pp. 181-184.
Data di pubblicazione: | 1979 |
Titolo: | Kinetics of hybridization to human DNA of heterogeneous nuclear RNA isolated from normal human lymphoblasts and acute leukemia blast cells. |
Autore/i: | Torelli, Giuseppe; Narni, Franco; Franchini, G; Donelli, A; Ferrari, Sergio; Calabretta, Bruno; Torelli, Umberto; Bosi, Paolo |
Autore/i UNIMORE: | |
Rivista: | |
Volume: | 5 |
Pagina iniziale: | 181 |
Pagina finale: | 184 |
Codice identificativo ISI: | WOS:A1979HJ86100009 |
Codice identificativo Scopus: | 2-s2.0-0018806057 |
Codice identificativo Pubmed: | 290855 |
Citazione: | Kinetics of hybridization to human DNA of heterogeneous nuclear RNA isolated from normal human lymphoblasts and acute leukemia blast cells / Torelli, Giuseppe; Narni, Franco; Franchini, G; Donelli, A; Ferrari, Sergio; Calabretta, Bruno; Torelli, Umberto; Bosi, Paolo. - In: MOLECULAR BIOLOGY REPORTS. - ISSN 0301-4851. - STAMPA. - 5(1979), pp. 181-184. |
Tipologia | Articolo su rivista |
File in questo prodotto:

I documenti presenti in Iris Unimore sono rilasciati con licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 3.0 Italia, salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris