The majority of neurons belonging to the central nervous system of the mollusc Planorbarius corneus is capable of neurite regeneration in vitro only in presence of factors released from the periesophageal ganglionic ring. Even each individual ganglion produces unknown stimulating factors sufficient for a complete neurite regeneration. The percentage of neurons showing neurite regeneration is nearly the same independent of ganglionic type and it increases following a rise in the concentration of promoting factors. We identified by RIA an insulin -like molecule among the released substances. Adding antisera against molluscan insulin -like neuropeptides to the culture medium we obtained an almost complete inhibition of neurite regeneration when the factors are released by cerebral or pedal ganglia. No inhibition occurs if the neural factors are released by visceroparietal ganglia.

Promotion and inhibition of neurite regeneration in cultured neurons / Sonetti, Dario; F., Bianchi; Sabatini, Maria Agnese; Baraldi, Enrica; Fratello, Bernardo. - In: NEUROSCIENCE LETTERS. - ISSN 0304-3940. - STAMPA. - non disponibile:(1992), pp. 105-105. ((Intervento presentato al convegno Fifth Meeting of the Italian Society of Neuroscience tenutosi a Modena nel 1-4 December 1992.

Promotion and inhibition of neurite regeneration in cultured neurons

SONETTI, Dario;SABATINI, Maria Agnese;BARALDI, Enrica;FRATELLO, Bernardo
1992

Abstract

The majority of neurons belonging to the central nervous system of the mollusc Planorbarius corneus is capable of neurite regeneration in vitro only in presence of factors released from the periesophageal ganglionic ring. Even each individual ganglion produces unknown stimulating factors sufficient for a complete neurite regeneration. The percentage of neurons showing neurite regeneration is nearly the same independent of ganglionic type and it increases following a rise in the concentration of promoting factors. We identified by RIA an insulin -like molecule among the released substances. Adding antisera against molluscan insulin -like neuropeptides to the culture medium we obtained an almost complete inhibition of neurite regeneration when the factors are released by cerebral or pedal ganglia. No inhibition occurs if the neural factors are released by visceroparietal ganglia.
non disponibile
105
105
Sonetti, Dario; F., Bianchi; Sabatini, Maria Agnese; Baraldi, Enrica; Fratello, Bernardo
Promotion and inhibition of neurite regeneration in cultured neurons / Sonetti, Dario; F., Bianchi; Sabatini, Maria Agnese; Baraldi, Enrica; Fratello, Bernardo. - In: NEUROSCIENCE LETTERS. - ISSN 0304-3940. - STAMPA. - non disponibile:(1992), pp. 105-105. ((Intervento presentato al convegno Fifth Meeting of the Italian Society of Neuroscience tenutosi a Modena nel 1-4 December 1992.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/746332
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact