EnglishSelected non-ionic surfactants of the polyoxyethylene ether series as well as selected bile acids elicit plasma clearing activity (PC) after oral heparin administration by action on the gastro-intestinal mucosa. Evidence obtained indicates that certain structural characteristics are needed for promoting heparin absorption, since this effect is observed with some but not all non-ionic detergents (cetyl and stearyl ethers but not lauryl) and bile components (deoxycholic, chenodeoxycholic and cholic acids, but not ursodeoxycholic or dehydrocholic acids or lecithin). It is suggested that a specific mechanism of action is involved.
Structural restriction in bile acids and non-ionic detergents for promotion of heparin absorption from rat gastro-intestinal tract / Guarini, Salvatore; Ferrari, William. - In: ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE. - ISSN 0003-9780. - STAMPA. - 27(1984), pp. 4-10.
| Data di pubblicazione: | 1984 |
| Titolo: | Structural restriction in bile acids and non-ionic detergents for promotion of heparin absorption from rat gastro-intestinal tract. |
| Autore/i: | Guarini, Salvatore; Ferrari, William |
| Autore/i UNIMORE: | |
| Rivista: | |
| Volume: | 27 |
| Pagina iniziale: | 4 |
| Pagina finale: | 10 |
| Codice identificativo ISI: | WOS:A1984TK09600001 |
| Codice identificativo Scopus: | 2-s2.0-0021240446 |
| Codice identificativo Pubmed: | 6497508 |
| Citazione: | Structural restriction in bile acids and non-ionic detergents for promotion of heparin absorption from rat gastro-intestinal tract / Guarini, Salvatore; Ferrari, William. - In: ARCHIVES INTERNATIONALES DE PHARMACODYNAMIE ET DE THERAPIE. - ISSN 0003-9780. - STAMPA. - 27(1984), pp. 4-10. |
| Tipologia | Articolo su rivista |
File in questo prodotto:
I documenti presenti in Iris Unimore sono rilasciati con licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 3.0 Italia, salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
Copyright © 2021