We undertook a series of in vitro studies to evaluate the effects of different doses and compounds of selenium on functional activities of human lymphocytes. The NK cell activity and the proliferation and antibody release by cultured lymphocytes were studied. Our studies suggest that an excess of Se may have a detrimental effect on certain immunological parameters. In addition, Se bioavailability more than absolute levels should be considered to better understand the Se role on immune system
Selenium interaction with human cell functions / Borella, Paola; Bargellini, Annalisa; V., Solfrini. - STAMPA. - 5:(1998), pp. 429-434. (Intervento presentato al convegno Fifth International Symposium on Metal Ions in Biology and Medicine tenutosi a Neuherberg-Munich nel May 8-10, 1998).
Selenium interaction with human cell functions
BORELLA, Paola;BARGELLINI, Annalisa;
1998
Abstract
We undertook a series of in vitro studies to evaluate the effects of different doses and compounds of selenium on functional activities of human lymphocytes. The NK cell activity and the proliferation and antibody release by cultured lymphocytes were studied. Our studies suggest that an excess of Se may have a detrimental effect on certain immunological parameters. In addition, Se bioavailability more than absolute levels should be considered to better understand the Se role on immune systemPubblicazioni consigliate
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