One of the possible strategy to study the relationships between the immune and the neuroendocrine system is to trace their evolutionary origin. In a previous study we showed that immunoreactive ACTH-and beta-endorphin (BE)-like molecules were present in the serum and in the phagocytic cells, i.e., spreading hemocites (sh).We hypothesized a possible biological role of ACTH and BE in chemotaxis and phagocytosis, and in some sort of stress reaction.
The «immune-mobile brain»: evolutionaryevidence / Ottaviani, Enzo; Caselgrandi, Eva; Bondi, Moreno; Cossarizza, Andrea; Monti, Daniela; Franceschi, Claudio. - In: ADVANCES IN NEUROIMMUNOLOGY. - ISSN 0960-5428. - STAMPA. - 1:(1991), pp. 27-39.
The «immune-mobile brain»: evolutionaryevidence.
OTTAVIANI, Enzo;CASELGRANDI, Eva;BONDI, Moreno;COSSARIZZA, Andrea;MONTI, Daniela;FRANCESCHI, Claudio
1991
Abstract
One of the possible strategy to study the relationships between the immune and the neuroendocrine system is to trace their evolutionary origin. In a previous study we showed that immunoreactive ACTH-and beta-endorphin (BE)-like molecules were present in the serum and in the phagocytic cells, i.e., spreading hemocites (sh).We hypothesized a possible biological role of ACTH and BE in chemotaxis and phagocytosis, and in some sort of stress reaction.
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