By means of semiquantitative immunocytochemistry and quantitative receptor autoradiography a correlation analysis has been performed on the pre- and post-synaptic features of enkephalin and beta-endorphin immunoreactive neuron systems of the 3- and 24-month-old male rat. A parallel disappearance of enkephalin- and beta-endorphin-like immunoreactivity and of the density of mu and delta opiate receptors is shown during ageing. Furthermore, the lack of an overall correlation between the amount of pre- and post-synaptic components of the enkephalin and beta-endorphin synapses give evidence for the existence of a volume type of transmission in such systems in the telencephalic, diencephalic and mesencephalic areas analysed.

A correlation analysis of the regional distribution of central enkephalin and beta-endorphin immunoreactive terminals and of opiate receptors in adult and old male rats. Evidence for the existence of two main types of communication in the central nervous system: the volume transmission and the wiring transmission / Agnati, Luigi Francesco; Fuxe, K; Zoli, Michele; Zini, Isabella; Toffano, G; Ferraguti, F.. - In: ACTA PHYSIOLOGICA SCANDINAVICA. - ISSN 0001-6772. - STAMPA. - 128:(1986), pp. 201-207.

A correlation analysis of the regional distribution of central enkephalin and beta-endorphin immunoreactive terminals and of opiate receptors in adult and old male rats. Evidence for the existence of two main types of communication in the central nervous system: the volume transmission and the wiring transmission.

AGNATI, Luigi Francesco;ZOLI, Michele;ZINI, Isabella;
1986

Abstract

By means of semiquantitative immunocytochemistry and quantitative receptor autoradiography a correlation analysis has been performed on the pre- and post-synaptic features of enkephalin and beta-endorphin immunoreactive neuron systems of the 3- and 24-month-old male rat. A parallel disappearance of enkephalin- and beta-endorphin-like immunoreactivity and of the density of mu and delta opiate receptors is shown during ageing. Furthermore, the lack of an overall correlation between the amount of pre- and post-synaptic components of the enkephalin and beta-endorphin synapses give evidence for the existence of a volume type of transmission in such systems in the telencephalic, diencephalic and mesencephalic areas analysed.
128
201
207
A correlation analysis of the regional distribution of central enkephalin and beta-endorphin immunoreactive terminals and of opiate receptors in adult and old male rats. Evidence for the existence of two main types of communication in the central nervous system: the volume transmission and the wiring transmission / Agnati, Luigi Francesco; Fuxe, K; Zoli, Michele; Zini, Isabella; Toffano, G; Ferraguti, F.. - In: ACTA PHYSIOLOGICA SCANDINAVICA. - ISSN 0001-6772. - STAMPA. - 128:(1986), pp. 201-207.
Agnati, Luigi Francesco; Fuxe, K; Zoli, Michele; Zini, Isabella; Toffano, G; Ferraguti, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/744394
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