Three propranolol analogues' bearing the oxygen ol the-OH group enclosed in a 1,4-dioxanic ring system,were synthetized.The lack of beta-blocking activity found for these compounds demonstrates theimportant role played by a free -OHgroup in the drug-receptor interaction.
SYNTHESIS AND PHARMACOLOGICAL EVALUATIONOF PROPRANOLOL-CYCLIC ANALOGUES / E., Castagnino; S., Corsano; G., Strappaghetti; Brasili, Livio; P., Gallucci. - In: IL FARMACO. EDIZIONE SCIENTIFICA. - ISSN 0430-0920. - STAMPA. - 9:(1983), pp. 680-???.
SYNTHESIS AND PHARMACOLOGICAL EVALUATIONOF PROPRANOLOL-CYCLIC ANALOGUES
BRASILI, Livio;
1983
Abstract
Three propranolol analogues' bearing the oxygen ol the-OH group enclosed in a 1,4-dioxanic ring system,were synthetized.The lack of beta-blocking activity found for these compounds demonstrates theimportant role played by a free -OHgroup in the drug-receptor interaction.
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
