Three WB4101 analogues, bearing system a 1,4-naphtodioxanic system, were svnthesized.. The decrease of alpha-blocking activity found for these compounds. showed that extension of aromatic area in the dioxanic mojety of such benzodioxanic deerivative, hinders the drug-receptor interaction.
SYNTHESIS AND PHARMACOLOGICAL EVALUATIONOF SOME V/84101 ANALOGUES BEARING ANAPHTODIOXANIC NUCLEUS / E., Castagnino; G., Strappaghetti; S., Corsano; P., Gallucci; Brasili, Livio; D., Giardina. - In: IL FARMACO. EDIZIONE SCIENTIFICA. - ISSN 0430-0920. - STAMPA. - 7:(1984), pp. ??-??.
SYNTHESIS AND PHARMACOLOGICAL EVALUATIONOF SOME V/84101 ANALOGUES BEARING ANAPHTODIOXANIC NUCLEUS
BRASILI, Livio;
1984
Abstract
Three WB4101 analogues, bearing system a 1,4-naphtodioxanic system, were svnthesized.. The decrease of alpha-blocking activity found for these compounds. showed that extension of aromatic area in the dioxanic mojety of such benzodioxanic deerivative, hinders the drug-receptor interaction.
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