Prospective area based study of group B Streptococcus infections Background Group B Streptococcus (GBS) is a leading cause of neonatal sepsis and meningitis in newborns Intrapartum administration of antibiotics to GBS colonized mothers reduces the rate of early-onset disease. Objectives To promote a common prevention strategy in an Italian region, to analyze clinical findings, trends of disease incidence and factors which determine the persistence of the disease. Methods Prospective, area-based study, during a 6 years period; all delivery units and regional laboratories involved in the study. Results A screening-based strategy was adopted by centres. The incidence of earlyonset disease was low with respect to European countries; most of residual cases were associated with the culture detection failure of organisms at 35-37 weeks of gestation. Meningitis was much more common among infants with late-onset disease. Both, early- and late-onset infections had no significant variations of disease incidence during the 6 years study period. Conclusions Prevention strategies reduced the rate and the severity of early-infections. Most residual cases were due to the culture detection failure of organisms at antenatal screening; additional efforts are therefore required to implement the strategy.

The network of surveillance of infections streptococcal B in Emilia-Romagna: Prevention of early infections [La rete di sorveglianza delle infezioni da Streptococco B nella Regione Emilia-Romagna: Prevenzione delle infezioni precoci] / Berardi, A.; Lugli, L.; Rossi, C.; Bidetti, M. L.; Calanca, F.; Casula, F.; China, M.; Chiossi, C.; Fazio, G. D.; Galuppi, E.; Gavioli, S.; Pedna, M. F.; Piepoli, M.; Ricci, L.; Sarti, M.; Simoni, A.; Ferrari, M.; Ferrari, Fabrizio. - In: QUADERNI ACP. - ISSN 2039-1374. - STAMPA. - 17:(2010), pp. 3-7.

The network of surveillance of infections streptococcal B in Emilia-Romagna: Prevention of early infections [La rete di sorveglianza delle infezioni da Streptococco B nella Regione Emilia-Romagna: Prevenzione delle infezioni precoci]

Berardi A.;FERRARI, Fabrizio
2010

Abstract

Prospective area based study of group B Streptococcus infections Background Group B Streptococcus (GBS) is a leading cause of neonatal sepsis and meningitis in newborns Intrapartum administration of antibiotics to GBS colonized mothers reduces the rate of early-onset disease. Objectives To promote a common prevention strategy in an Italian region, to analyze clinical findings, trends of disease incidence and factors which determine the persistence of the disease. Methods Prospective, area-based study, during a 6 years period; all delivery units and regional laboratories involved in the study. Results A screening-based strategy was adopted by centres. The incidence of earlyonset disease was low with respect to European countries; most of residual cases were associated with the culture detection failure of organisms at 35-37 weeks of gestation. Meningitis was much more common among infants with late-onset disease. Both, early- and late-onset infections had no significant variations of disease incidence during the 6 years study period. Conclusions Prevention strategies reduced the rate and the severity of early-infections. Most residual cases were due to the culture detection failure of organisms at antenatal screening; additional efforts are therefore required to implement the strategy.
2010
17
3
7
The network of surveillance of infections streptococcal B in Emilia-Romagna: Prevention of early infections [La rete di sorveglianza delle infezioni da Streptococco B nella Regione Emilia-Romagna: Prevenzione delle infezioni precoci] / Berardi, A.; Lugli, L.; Rossi, C.; Bidetti, M. L.; Calanca, F.; Casula, F.; China, M.; Chiossi, C.; Fazio, G. D.; Galuppi, E.; Gavioli, S.; Pedna, M. F.; Piepoli, M.; Ricci, L.; Sarti, M.; Simoni, A.; Ferrari, M.; Ferrari, Fabrizio. - In: QUADERNI ACP. - ISSN 2039-1374. - STAMPA. - 17:(2010), pp. 3-7.
Berardi, A.; Lugli, L.; Rossi, C.; Bidetti, M. L.; Calanca, F.; Casula, F.; China, M.; Chiossi, C.; Fazio, G. D.; Galuppi, E.; Gavioli, S.; Pedna, M. F.; Piepoli, M.; Ricci, L.; Sarti, M.; Simoni, A.; Ferrari, M.; Ferrari, Fabrizio
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/743291
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