EnglishStretching-yawning syndrome (SYS) and penile erections (PE) are typical components of the behavioral picture induced by intracerebroventricular (i.c.v.) injection of ACTH 1-24. The present study shows that pretreatment with alpha-difluoromethylornithine (DFMO), and irreversible inhibitor of mammalian ornithine decarboxylase (ODC), antagonizes these behavioral effects in a dose-dependent way, in rats. These results suggest that ODC and polyamines may play a role in the transduction and transmission of receptor-mediated signals.
| Data di pubblicazione: | 1984 |
| Titolo: | Effect of alpha-difluoromethylornithine (DFMO) on the behavioral syndrome induced by intracerebroventricular injection of ACTH 1-24, in rats. |
| Autore/i: | Genedani, Susanna; Bernardi, Mara; Bertolini, Alfio |
| Autore/i UNIMORE: | |
| Rivista: | |
| Volume: | 4 |
| Pagina iniziale: | 247 |
| Pagina finale: | 250 |
| Codice identificativo ISI: | WOS:A1984SU59400007 |
| Codice identificativo Scopus: | 2-s2.0-0021264319 |
| Codice identificativo Pubmed: | 6087190 |
| Citazione: | Effect of alpha-difluoromethylornithine (DFMO) on the behavioral syndrome induced by intracerebroventricular injection of ACTH 1-24, in rats / Genedani, Susanna; Bernardi, Mara; Bertolini, Alfio. - In: NEUROPEPTIDES. - ISSN 0143-4179. - STAMPA. - 4(1984), pp. 247-250. |
| Tipologia | Articolo su rivista |
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