GH treatment improves height growth rate in our patients, maintaining a significant efficacy along 2 years. Our results confirm that APA are detectable in CD patients with GHD suggesting an involvement of autoimmune mechanisms in the lack of height improvement after GFD. These patients could benefit by precocious hormonal therapy, interrupting the progression towards a stable clinical disease.
The effect of growth hormone (GH) treatment in children with celiac disease (CD), antipituitary antibodies (APA) and growth hormonedeficiency (GHD) / Iughetti, Lorenzo; A., De Bellis; Predieri, Barbara; A., Bellastella; A., Bizzarro; S., Madeo; L., Saviano; F., Balli; S., Bernasconi. - In: HORMONE RESEARCH. - ISSN 0301-0163. - STAMPA. - 64 (S4):(2006), pp. 152-152. (Intervento presentato al convegno 45th Meeting dell’European Society of Pediatric Endocrinology, tenutosi a Rotterdam 30 giugno-3 luglio 2006, nel Rotterdam 30 giugno-3 luglio 2006,).
The effect of growth hormone (GH) treatment in children with celiac disease (CD), antipituitary antibodies (APA) and growth hormonedeficiency (GHD)
IUGHETTI, Lorenzo;PREDIERI, Barbara;
2006
Abstract
GH treatment improves height growth rate in our patients, maintaining a significant efficacy along 2 years. Our results confirm that APA are detectable in CD patients with GHD suggesting an involvement of autoimmune mechanisms in the lack of height improvement after GFD. These patients could benefit by precocious hormonal therapy, interrupting the progression towards a stable clinical disease.
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