The prevalence of thyroid disorders has been studied in patients with chronic hepatitis C virus (HCV) infection by many studies. In general, thyroid dysfunction in chronic C hepatitis may include all forms of thyroid alterations, i.e. hypothyroidism and hyperthyroidism, Hashimoto's disease and isolated increases in antithyroid autoantibodies. The prevalence of various thyroid disorders and serum anti-thyroid autoantibodies is generally higher in chronic hepatitis type C than in hepatitis B or D or control series. The results of most studies in patients with hepatitis C confirm a higher prevalence of autoimmune thyroid involvement and hypothyroidism than in controls. More recently, some epidemiological studies have suggested a possible association between HCV and thyroid cancer. These last data need to be confirmed by other studies, but seem to be sufficient to suggest careful thyroid monitoring during the follow-up of patients with HCV infection.
Extrahepatic manifestations of hepatitis C virus: the thyroid disorders / Antonelli, A; Ferri, Clodoveo; Fallahi, P; Ferrari, Silvia Martina; Ghinoi, A; Mascia, Maria Teresa; Ferrannini, E.. - In: RECENTI PROGRESSI IN MEDICINA. - ISSN 2038-1840. - STAMPA. - 96:(2005), pp. 378-381.