Bone mass measurements were performed in a group of 100 healthy women (ages 22-74 years) with both a densitometric technique measuring ultrasound bone velocity (UBV) at the distal metaphyses of the first phalanges of the hand and single-photon absorptiometry (SPA) applied at the distal forearm and ultradistal radius. A significant (p < 0.00001) difference was found in both UBV and bone mineral density (BMD) values between premenopausal and postmenopausal women. Simple regression analysis showed a highly significant relationship (p < 0.0001) between UBV measured at proximal phalanges and BMD measured at the distal forearm (r = 0.693) and ultradistal radius (r = 0.643). There was no correlation between age and both UBV and BMD in premenopausal women. By contrast, a significant correlation was found between UBV and age in postmenopausal women (p < 0.0001: r = 0.510). A similar correlation with age was found for BMD measured at the distal forearm (p < 0.0001; r = 0.458) and ultradistal radius (p < 0.0002: r = 0.435). Changes of UBV were also significantly related to years since menopause (p < 0.0001: r = 0.526). as were BMD variations at the distal forearm (p <: 0.0001; r = 0.451) and ultradistal radius (p < 0.008: r = 0.402). The reproducibility of the methods (coefficient of variation) was 0.46% for UBV and 0.92% for SPA. Our findings seem to indicate that UBV measured at the phalanges may have the same clinical applications as BMD measured at the distal forearm and ultradistal radius.

Comparison between a new ultrasound densitometer and single photon absorptiometry / Murgia, C; Cagnacci, Angelo; Paoletti, Am; Pilia, L; Meloni, A; Melis, Gb. - In: MENOPAUSE. - ISSN 1072-3714. - STAMPA. - 3(3)(1996), pp. 149-153.

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