Follicular fluid sex-steroids, insulin-like growth factor-I (IGF-I), IGF-I binding protein (IGF-I-BP) and epidermal growth factor were investigated in patients with polycystic ovaries and normally ovulating women, following ovulation induction with gonadotrophins or growth hormone plus gonadotrophins. Growth hormone supplementation enhanced the ovarian response to gonadotrophins, and significantly increased follicular fluid IGF-I in both groups, without affecting follicular fluid epidermal growth factor; growth hormone supplementation significantly decreased follicular fluid androstenedione in both groups.

Effects of growth hormone administration in addition to gonadotrophins in normally ovulating women and polycystic ovary syndrome (PCO) patients / Volpe, Annibale; P. G., Artini; A., Barreca; F., Minuto; G., Coukos; A. R., Genazzani. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - STAMPA. - 7:(1992), pp. 1347-1352. [10.1093/oxfordjournals.humrep.a137571]

Effects of growth hormone administration in addition to gonadotrophins in normally ovulating women and polycystic ovary syndrome (PCO) patients.

VOLPE, Annibale;
1992

Abstract

Follicular fluid sex-steroids, insulin-like growth factor-I (IGF-I), IGF-I binding protein (IGF-I-BP) and epidermal growth factor were investigated in patients with polycystic ovaries and normally ovulating women, following ovulation induction with gonadotrophins or growth hormone plus gonadotrophins. Growth hormone supplementation enhanced the ovarian response to gonadotrophins, and significantly increased follicular fluid IGF-I in both groups, without affecting follicular fluid epidermal growth factor; growth hormone supplementation significantly decreased follicular fluid androstenedione in both groups.
1992
Inglese
7
1347
1352
WOS:A1992KF96500003
2-s2.0-0027093794
1283981
Adult, Androstenedione; biosynthesis, Carrier Proteins; biosynthesis, Drug Synergism, Epidermal Growth Factor; biosynthesis, Estradiol; biosynthesis, Female, Follicular Fluid; chemistry/drug effects, Gonadotropins; pharmacology, Growth Hormone; pharmacology, Humans, Infertility; Female; drug therapy, Insulin-Like Growth Factor Binding Protein 1, Insulin-Like Growth Factor I; biosynthesis, Ovulation Induction; methods, Ovulation; drug effects, Polycystic Ovary Syndrome; drug therapy, Progesterone; biosynthesis
none
info:eu-repo/semantics/article
Contributo su RIVISTA::Articolo su rivista
262
Effects of growth hormone administration in addition to gonadotrophins in normally ovulating women and polycystic ovary syndrome (PCO) patients / Volpe, Annibale; P. G., Artini; A., Barreca; F., Minuto; G., Coukos; A. R., Genazzani. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - STAMPA. - 7:(1992), pp. 1347-1352. [10.1093/oxfordjournals.humrep.a137571]
Volpe, Annibale; P. G., Artini; A., Barreca; F., Minuto; G., Coukos; A. R., Genazzani
6
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/741294
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