Cadmium, zinc and copper levels in blood, hair and urine were measured in hypertensives and matched normotensives. A significant increase of cadmium in blood was found in relation to hypertension, particularly when subjects were non smokers. Furthermore, cadmium levels in blood and the ratio Cd/Zn in blood and urine appeared to be significantly and positively related to both systolic and diastolic blood pressure levels. Copper excretion in urine of hypertensives and normotensives was 14.1 and 9.2 µg/g creat., respectively, and the difference was statistically significant. As far as zinc-dependent enzymes were concerned, alkaline phosphatase activity was significantly lower in both untreated and treated hypertensives compared with their controls.
Cadmium, zinc, and copper in hypertension / Borella, Paola; Bergomi, Margherita; Fantuzzi, Guglielmina; Rovesti, Sergio; Vivoli, Gianfranco. - STAMPA. - 2:(1987), pp. 89-91. (Intervento presentato al convegno International Conference: Heavy metals in the environment tenutosi a New Orleans, Louisiana, USA nel September 15-18, 1987).
Cadmium, zinc, and copper in hypertension
BORELLA, Paola;BERGOMI, Margherita;FANTUZZI, Guglielmina;ROVESTI, Sergio;VIVOLI, Gianfranco
1987
Abstract
Cadmium, zinc and copper levels in blood, hair and urine were measured in hypertensives and matched normotensives. A significant increase of cadmium in blood was found in relation to hypertension, particularly when subjects were non smokers. Furthermore, cadmium levels in blood and the ratio Cd/Zn in blood and urine appeared to be significantly and positively related to both systolic and diastolic blood pressure levels. Copper excretion in urine of hypertensives and normotensives was 14.1 and 9.2 µg/g creat., respectively, and the difference was statistically significant. As far as zinc-dependent enzymes were concerned, alkaline phosphatase activity was significantly lower in both untreated and treated hypertensives compared with their controls.
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