Porcine follicular fluid was found to contain gastrin-releasing peptide (GRP) by radioimmunoassay. High pressure liquid chromatography of the extracted material showed two peaks of GRP immunoreactivity that closely resembled the C-terminal fragments of GRP, GRP18-27 and GRP14-27. Immunohistochemical studies revealed specific staining for GRP in the granulosa cells of adult porcine ovary. These results demonstrate the presence of substances which behave like authentic GRP-like peptides in porcine ovary and follicular fluid and suggest that these peptides may play a paracrine and/or autocrine role in the regulation of the ovarian function.

Gastrin-releasing peptide-like immunoreactivity in porcine follicular fluid and ovary / L., Gnessi; S., Altamura; M., Arizzi; C., Tei; C. L., Torre; V., Bonifacio; Facchinetti, Fabio; G., Spera. - In: MOLECULAR AND CELLULAR ENDOCRINOLOGY. - ISSN 0303-7207. - STAMPA. - 66:(1989), pp. 115-118.

Gastrin-releasing peptide-like immunoreactivity in porcine follicular fluid and ovary.

FACCHINETTI, Fabio;
1989

Abstract

Porcine follicular fluid was found to contain gastrin-releasing peptide (GRP) by radioimmunoassay. High pressure liquid chromatography of the extracted material showed two peaks of GRP immunoreactivity that closely resembled the C-terminal fragments of GRP, GRP18-27 and GRP14-27. Immunohistochemical studies revealed specific staining for GRP in the granulosa cells of adult porcine ovary. These results demonstrate the presence of substances which behave like authentic GRP-like peptides in porcine ovary and follicular fluid and suggest that these peptides may play a paracrine and/or autocrine role in the regulation of the ovarian function.
1989
66
115
118
Gastrin-releasing peptide-like immunoreactivity in porcine follicular fluid and ovary / L., Gnessi; S., Altamura; M., Arizzi; C., Tei; C. L., Torre; V., Bonifacio; Facchinetti, Fabio; G., Spera. - In: MOLECULAR AND CELLULAR ENDOCRINOLOGY. - ISSN 0303-7207. - STAMPA. - 66:(1989), pp. 115-118.
L., Gnessi; S., Altamura; M., Arizzi; C., Tei; C. L., Torre; V., Bonifacio; Facchinetti, Fabio; G., Spera
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/740730
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