Sixty patients with stage IIIA and IIIB breast cancer have been treated with a combined modality approach including induction chemotherapy, surgery and adjuvant chemotherapy: 74.5\% of patients achieved an objective response after 3 cycles of induction chemotherapy, and 98.3\% of patients were rendered disease-free after induction chemotherapy and surgery or radiotherapy; at 4 years, actuarial survival and disease-free survival are 71.5\% and 43\%, respectively. These results are significantly better than our historical control, and locally advanced breast cancer must now be considered a curable disease when treated with an aggressive multimodal approach.
The role of surgery in the combined treatment of locally advanced breast cancer / G., Canavese; A., Catturich; G., Battistini; C., Caroti; P., Pronzato; G., Gardin; D., Amoroso; G., Bertelli; Conte, Pierfranco; S., Tomao. - In: ONCOLOGY. - ISSN 0030-2414. - STAMPA. - 46:(1989), pp. 353-356.
The role of surgery in the combined treatment of locally advanced breast cancer.
CONTE, Pierfranco;
1989
Abstract
Sixty patients with stage IIIA and IIIB breast cancer have been treated with a combined modality approach including induction chemotherapy, surgery and adjuvant chemotherapy: 74.5\% of patients achieved an objective response after 3 cycles of induction chemotherapy, and 98.3\% of patients were rendered disease-free after induction chemotherapy and surgery or radiotherapy; at 4 years, actuarial survival and disease-free survival are 71.5\% and 43\%, respectively. These results are significantly better than our historical control, and locally advanced breast cancer must now be considered a curable disease when treated with an aggressive multimodal approach.
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