The paraventricular nucleus (PVH) of the hypothalamus is a key region for the control of food intake. It presents a very high neuropeptide Y (NPY)-like positive innervation. In this paper we have studied the modifications of NPY-positive innervation in the PVH of 72 h starved rats vs control rats by means of semiquantitative immunocytochemistry. We observed a significant increase of NPY-like immunoreactivity in fasting rats. This result suggests a physiological role of NPY in the food intake regulation at the PVH level
Increase of neuropeptide Y-like immunoreactivity in the paraventricular nucleus of fasting rats / Calzá, L; Giardino, L; Battistini, Nino Carlo; Zanni, M; Galetti, S; Protopapa, F; Velardo, A.. - In: NEUROSCIENCE LETTERS. - ISSN 0304-3940. - STAMPA. - 104(1-2):(1989), pp. 99-104.
Increase of neuropeptide Y-like immunoreactivity in the paraventricular nucleus of fasting rats.
BATTISTINI, Nino Carlo;
1989-01-01
Abstract
The paraventricular nucleus (PVH) of the hypothalamus is a key region for the control of food intake. It presents a very high neuropeptide Y (NPY)-like positive innervation. In this paper we have studied the modifications of NPY-positive innervation in the PVH of 72 h starved rats vs control rats by means of semiquantitative immunocytochemistry. We observed a significant increase of NPY-like immunoreactivity in fasting rats. This result suggests a physiological role of NPY in the food intake regulation at the PVH level
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