The authors review the role, clinico-serological correlations and the putative pathogenetic relevance of a number of immunological parameters in essential mixed cryoglobulinemia. On the whole, in spite of the fact that levels of cryoglobulins, immune complexes, complement as well as reticuloendothelial splenic function are frequently abnormal in this condition, they are generally poorly correlated with clinical features. Therefore, it is postulated that this apparent discrepancy may either be due to the contemporary presence in the same serum of many types of immune complexes with different toxicity, or to the influence of rheumatoid factor on the nature of circulating immune complexes

Cryoglobulins and immune complexes in essential mixed cryoglobulinemia / Bombardieri, S; Ferri, Clodoveo; Migliorini, P; Pontrandolfo, A; Puccetti, A; Vitali, C; Pasero, G.. - In: LA RICERCA IN CLINICA E IN LABORATORIO. - ISSN 0390-5748. - STAMPA. - 16:(1986), pp. 281-288.

Cryoglobulins and immune complexes in essential mixed cryoglobulinemia

FERRI, Clodoveo;
1986

Abstract

The authors review the role, clinico-serological correlations and the putative pathogenetic relevance of a number of immunological parameters in essential mixed cryoglobulinemia. On the whole, in spite of the fact that levels of cryoglobulins, immune complexes, complement as well as reticuloendothelial splenic function are frequently abnormal in this condition, they are generally poorly correlated with clinical features. Therefore, it is postulated that this apparent discrepancy may either be due to the contemporary presence in the same serum of many types of immune complexes with different toxicity, or to the influence of rheumatoid factor on the nature of circulating immune complexes
1986
16
281
288
Cryoglobulins and immune complexes in essential mixed cryoglobulinemia / Bombardieri, S; Ferri, Clodoveo; Migliorini, P; Pontrandolfo, A; Puccetti, A; Vitali, C; Pasero, G.. - In: LA RICERCA IN CLINICA E IN LABORATORIO. - ISSN 0390-5748. - STAMPA. - 16:(1986), pp. 281-288.
Bombardieri, S; Ferri, Clodoveo; Migliorini, P; Pontrandolfo, A; Puccetti, A; Vitali, C; Pasero, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/738349
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