Two innovative glass compositions based on the commonly used 45S5 Bioglass® were developed by increasing the calcium quan- tity and replacing the sodium oxide with a specific content of potassium oxide. The new glasses, named BG_Ca/K and BG_Ca/Mix, can be prepared using a conventional melting process and show a very low tendency to crystallize. Thanks to this peculiarity, BG_Ca/K and BG_Ca/Mix powders can be sintered at a relatively low temperature (800°C) to obtain sam- ples of high compactness and bioactivity, since their amorphous nature is preserved. Consequently, the proposed glasses are perfect for making specific products such as scaffolds or hydroxyapatite-based composites. Furthermore, the relatively low alkali amount in the new compositions gives rise to a slow ion leaching in simulated body fluid, thus avoiding abrupt changes in pH that can damage osteoblasts or negatively affect their behavior.

Low temperature sintering of innovative bioactive glasses / Bellucci, Devis; Sola, Antonella; Cannillo, Valeria. - In: JOURNAL OF THE AMERICAN CERAMIC SOCIETY. - ISSN 0002-7820. - STAMPA. - 95(2012), pp. 1313-1319. [10.1111/j.1551-2916.2012.05100.x]

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