We pooled data from 17 studies (allocating 3048 patients to BMS and 3392 to nine different DES). Indirect head-to-head comparison of sirolimus-eluting Cypher (N=1007) vs. polymeric paclitaxel-eluting Taxus (N=959) showed nonsignificant differences in TLR [OR=0.8 (0.5–1.4), p=0.45] but significant reductions in BRR favoring Cypher [OR=0.3 (0.1–0.6), p<0.001]. Everolimus-eluting stents appeared noninferior to Cypher or Taxus (p>0.50 for both TLR and BRR). Actinomycin-, mycophenolate-, and apolymeric paclitaxel-eluting stents (PES) all proved significantly worse than Cypher or Taxus for TLR or BRR.ConclusionNotwithstanding its inherent limitations, the present metaanalysis confirms the effectiveness of both Cypher and Taxus, supports the promising role of everolimus-eluting stents, and suggests the significant inferiority of most other devices. These post hoc findings, albeit intriguing, await prospective confirmation
Adjusted indirect comparison of intracoronary drug-eluting stents: evidence from a metaanalysis of randomized bare-metal-stent-controlled trials / BIONDI ZOCCAI, Giuseppe; Agostoni, P; Abbate, A; Testa, L; Burzotta, F; Lotrionte, M; Crea, F; Biasucci, Lm; Vetrovec, Gw; Colombo, A.. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - ELETTRONICO. - 100(2005), pp. 119-123.
Data di pubblicazione: | 2005 |
Titolo: | Adjusted indirect comparison of intracoronary drug-eluting stents: evidence from a metaanalysis of randomized bare-metal-stent-controlled trials. |
Autore/i: | BIONDI ZOCCAI, Giuseppe; Agostoni, P; Abbate, A; Testa, L; Burzotta, F; Lotrionte, M; Crea, F; Biasucci, Lm; Vetrovec, Gw; Colombo, A. |
Autore/i UNIMORE: | |
Rivista: | |
Volume: | 100 |
Pagina iniziale: | 119 |
Pagina finale: | 123 |
Codice identificativo ISI: | WOS:000228772100017 |
Codice identificativo Scopus: | 2-s2.0-20144389227 |
Codice identificativo Pubmed: | 15820294 |
Citazione: | Adjusted indirect comparison of intracoronary drug-eluting stents: evidence from a metaanalysis of randomized bare-metal-stent-controlled trials / BIONDI ZOCCAI, Giuseppe; Agostoni, P; Abbate, A; Testa, L; Burzotta, F; Lotrionte, M; Crea, F; Biasucci, Lm; Vetrovec, Gw; Colombo, A.. - In: INTERNATIONAL JOURNAL OF CARDIOLOGY. - ISSN 0167-5273. - ELETTRONICO. - 100(2005), pp. 119-123. |
Tipologia | Articolo su rivista |
File in questo prodotto:
File | Descrizione | Tipologia | |
---|---|---|---|
1-s2.0-S0167527304006898-main.pdf | Post-print dell'autore (bozza post referaggio) | Administrator |

I documenti presenti in Iris Unimore sono rilasciati con licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 3.0 Italia, salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris