Eosinophilic fasciitis (EF) is a rare disease characterized by symmetrical thickness and hardening of the skin, especially localized to forearms and thorax, with eosinophilia. Corticosteroids represent the first-line therapy, even if some patients are scarcely responsive and/or may develop important side effects due to long-term treatment. Here, we describe three cases of EF, two of them refractory to previous steroid therapy, successfully treated with D-penicillamine. The present clinical observations together with the updated review of the literature suggest usefulness of D-penicillamine in EF patients, as well as its potential steroid-sparing value.

D-penicillamine in the treatment of eosinophilic fasciitis: case reports and review of the literature / Manzini, C. U.; Sebastiani, Marco; Giuggioli, D.; Manfredi, Andreina Teresa; Colaci, Michele; Cesinaro, A. M.; Ferri, Clodoveo. - In: CLINICAL RHEUMATOLOGY. - ISSN 0770-3198. - STAMPA. - 31:1(2012), pp. 183-187. [10.1007/s10067-011-1866-3]

D-penicillamine in the treatment of eosinophilic fasciitis: case reports and review of the literature.

SEBASTIANI, Marco;D. Giuggioli;MANFREDI, Andreina Teresa;COLACI, Michele;FERRI, Clodoveo
2012

Abstract

Eosinophilic fasciitis (EF) is a rare disease characterized by symmetrical thickness and hardening of the skin, especially localized to forearms and thorax, with eosinophilia. Corticosteroids represent the first-line therapy, even if some patients are scarcely responsive and/or may develop important side effects due to long-term treatment. Here, we describe three cases of EF, two of them refractory to previous steroid therapy, successfully treated with D-penicillamine. The present clinical observations together with the updated review of the literature suggest usefulness of D-penicillamine in EF patients, as well as its potential steroid-sparing value.
2012
31
1
183
187
D-penicillamine in the treatment of eosinophilic fasciitis: case reports and review of the literature / Manzini, C. U.; Sebastiani, Marco; Giuggioli, D.; Manfredi, Andreina Teresa; Colaci, Michele; Cesinaro, A. M.; Ferri, Clodoveo. - In: CLINICAL RHEUMATOLOGY. - ISSN 0770-3198. - STAMPA. - 31:1(2012), pp. 183-187. [10.1007/s10067-011-1866-3]
Manzini, C. U.; Sebastiani, Marco; Giuggioli, D.; Manfredi, Andreina Teresa; Colaci, Michele; Cesinaro, A. M.; Ferri, Clodoveo
File in questo prodotto:
File Dimensione Formato  
Articolo penicillamina.pdf

Solo gestori archivio

Tipologia: Versione pubblicata dall'editore
Dimensione 118.28 kB
Formato Adobe PDF
118.28 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/705345
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 19
  • ???jsp.display-item.citation.isi??? 15
social impact