The effect of flaxseed oil rich in linolenic acid (ALA), and a mixed oil (flaxseed oil and fish oil) rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on the lipid clearance and peroxisome proliferator activated receptors (PPARs) in liver and adipose tissue of rats fed for 30 days with the two oils was evaluated. The results showed that after treatment with the mixed oil the hematic triacylglycerol content was significantly decreased compared to control animals. Regarding the tissue distribution of the major omega-3 fatty acids, both oils were able to increase ALA, EPA, docosapentaenoic acid (DPA) in liver and adipose tissue; and DHA solely in the adipose tissue. Finally the treatment with either flaxseed or mixed oil increased hepatic PPAR-γ expression but only the mixed oil enhanced the hepatic expression of PPAR-α. No effect on adipose tissue PPAR-γ expression was observed with both oils’ treatment.

n-3 Dietary supplementation and lipid metabolism: Differences between vegetable- and fish-derived oils / Campioli, Enrico; Rustichelli, Cecilia; Avallone, Rossella. - In: JOURNAL OF FUNCTIONAL FOODS. - ISSN 1756-4646. - ELETTRONICO. - 4:1(2012), pp. 207-212. [10.1016/j.jff.2011.10.006]

n-3 Dietary supplementation and lipid metabolism: Differences between vegetable- and fish-derived oils

CAMPIOLI, Enrico;RUSTICHELLI, Cecilia;AVALLONE, Rossella
2012

Abstract

The effect of flaxseed oil rich in linolenic acid (ALA), and a mixed oil (flaxseed oil and fish oil) rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on the lipid clearance and peroxisome proliferator activated receptors (PPARs) in liver and adipose tissue of rats fed for 30 days with the two oils was evaluated. The results showed that after treatment with the mixed oil the hematic triacylglycerol content was significantly decreased compared to control animals. Regarding the tissue distribution of the major omega-3 fatty acids, both oils were able to increase ALA, EPA, docosapentaenoic acid (DPA) in liver and adipose tissue; and DHA solely in the adipose tissue. Finally the treatment with either flaxseed or mixed oil increased hepatic PPAR-γ expression but only the mixed oil enhanced the hepatic expression of PPAR-α. No effect on adipose tissue PPAR-γ expression was observed with both oils’ treatment.
2012
4
1
207
212
n-3 Dietary supplementation and lipid metabolism: Differences between vegetable- and fish-derived oils / Campioli, Enrico; Rustichelli, Cecilia; Avallone, Rossella. - In: JOURNAL OF FUNCTIONAL FOODS. - ISSN 1756-4646. - ELETTRONICO. - 4:1(2012), pp. 207-212. [10.1016/j.jff.2011.10.006]
Campioli, Enrico; Rustichelli, Cecilia; Avallone, Rossella
File in questo prodotto:
File Dimensione Formato  
2012 J Functional Foods Enrico.pdf

Accesso riservato

Tipologia: Versione pubblicata dall'editore
Dimensione 321.28 kB
Formato Adobe PDF
321.28 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/705147
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 21
  • ???jsp.display-item.citation.isi??? 23
social impact