AbstractObjective: The aims of this work were to histologically examine the healing of mineralized human bone allograft (MHBA) in sinus augmentation for elevating a severe maxillary atrophy ridge (2mm residual ridge height) and to correlate the results to the sinus cavity size.Material and methods: A two-stage protocol was conducted in 23 patients, all having crestal bone 2mm. A mixture of 80/20 cortical/cancellous of MHBA particles was used to augment sinus using the lateral window approach in narrow (NS; o15mm bucco-palatal distance) and wide (WS; 15mm bucco-palatal distance) sinuses, based upon computerized tomography (CT) assessment. A bone core biopsy was taken at implant placement, 6 and 9 months after surgery. Microradiography, histology and histochemistry of methacrylate-embedded sections were performed to analyze and to evaluate the bone and graft amount.Results: Newly formed bone around MBHA particles was found in all 28 biopsies. Bone showed a woven structure at 6 months after surgery and a lamellar structure 9 months after surgery. At 6 months after surgery, the 13 NS and 15 WS had 30.5 8.8% and 20.7 4.9% mean SD bone formation, respectively. At 9 months after surgery, it was 38.8 7% (NS) and 30.7 3% (WS). Residual graft was about 16% (6 months) and 6% (9 months), in both NS and WS. The Mann–Whitney test showed agreater bone formation in NS than in WS (Po0.005).Conclusions: The used 80/20 MHBA mixture appears to promote, in the severe atrophic maxilla, a satisfactory bone formation. Our results prove that the larger the sinus, the longer the maturationtime needed to achieve a suitable amount of new bone formation.
Atrophic maxillary floor augmentation by mineralized human bone allograft in sinuses of different size: an histologic and histomorphometric analysis / C. M., Soardi; S., Spinato; Zaffe, Davide; H. L., Wang. - In: CLINICAL ORAL IMPLANTS RESEARCH. - ISSN 1600-0501. - STAMPA. - 22(2011), pp. 560-566.
Data di pubblicazione: | 2011 |
Titolo: | Atrophic maxillary floor augmentation by mineralized human bone allograft in sinuses of different size: an histologic and histomorphometric analysis. |
Autore/i: | C. M., Soardi; S., Spinato; Zaffe, Davide; H. L., Wang |
Autore/i UNIMORE: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/j.1600-0501.2010.02034.x |
Rivista: | |
Volume: | 22 |
Pagina iniziale: | 560 |
Pagina finale: | 566 |
Codice identificativo ISI: | WOS:000289253200016 |
Codice identificativo Scopus: | 2-s2.0-79953690493 |
Codice identificativo Pubmed: | 21143532 |
Citazione: | Atrophic maxillary floor augmentation by mineralized human bone allograft in sinuses of different size: an histologic and histomorphometric analysis / C. M., Soardi; S., Spinato; Zaffe, Davide; H. L., Wang. - In: CLINICAL ORAL IMPLANTS RESEARCH. - ISSN 1600-0501. - STAMPA. - 22(2011), pp. 560-566. |
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