Aim: aim of the study is to evaluate correlations between incidental thyroid carcinoma (ITC) and benign thyroid pathologies (BTP), to determine the most represented histotype and to point out the total thyroidectomy’s possible advantages in terms of radicality, follow-up management and incidence of complications.Materials and Methods: during 10 years, 739 patients underwent thyroid surgery for BTP. Fine needle biopsy (FNAB) was negative in all cases; 503 total thyroidectomies(TT), 5 subtotal thyroidectomies(ST) and 231 emithyroidectomies(ET) were performed.Results: the specimens pathological examination revealed the presence of a ITC in 82 patients (11,1%); the prevalent histotype was the papillary one with a less than 1cm diameter in almost the totality of cases but with nodes metastasis in the 3,6% of cases. Complications were detected in 117 patients with a morbidity rate of 15,8%. Discussion: in our study the ITC prevalence was of 11,1% similar to literature with a higher incidence in patients affected by multinodular than uninodular goiter. No statistical significant differences were found between euthyroid and toxic pathologies. In our series hyperthyroidism doesn’t seem to hold a protective role towards the ITC onset. Conclusions: The ITC incidence is relevant; the prevalent histotype is papillary and nodes metastasis are present even if in a low percentage of cases. Besides, the complications of TT are similar to conservative procedures. The recurrence of goiter and ITC require a second surgical procedure, with a higher risk of complications. So we can claim that the standard surgical treatment of bilateral PBT would be represented by TT.

Incidental thyroid carcinoma (ITC): a retrospective study in a series of 737 patients treated for benign disease / Gelmini, Roberta; Franzoni, Chiara; Pavesi, Erica; Cabry, Francesca; Saviano, Massimo. - In: ANNALI ITALIANI DI CHIRURGIA. - ISSN 0003-469X. - STAMPA. - 6:(2010), pp. 421-427.

Incidental thyroid carcinoma (ITC): a retrospective study in a series of 737 patients treated for benign disease

GELMINI, Roberta;FRANZONI, Chiara;PAVESI, Erica;CABRY, Francesca;SAVIANO, Massimo
2010

Abstract

Aim: aim of the study is to evaluate correlations between incidental thyroid carcinoma (ITC) and benign thyroid pathologies (BTP), to determine the most represented histotype and to point out the total thyroidectomy’s possible advantages in terms of radicality, follow-up management and incidence of complications.Materials and Methods: during 10 years, 739 patients underwent thyroid surgery for BTP. Fine needle biopsy (FNAB) was negative in all cases; 503 total thyroidectomies(TT), 5 subtotal thyroidectomies(ST) and 231 emithyroidectomies(ET) were performed.Results: the specimens pathological examination revealed the presence of a ITC in 82 patients (11,1%); the prevalent histotype was the papillary one with a less than 1cm diameter in almost the totality of cases but with nodes metastasis in the 3,6% of cases. Complications were detected in 117 patients with a morbidity rate of 15,8%. Discussion: in our study the ITC prevalence was of 11,1% similar to literature with a higher incidence in patients affected by multinodular than uninodular goiter. No statistical significant differences were found between euthyroid and toxic pathologies. In our series hyperthyroidism doesn’t seem to hold a protective role towards the ITC onset. Conclusions: The ITC incidence is relevant; the prevalent histotype is papillary and nodes metastasis are present even if in a low percentage of cases. Besides, the complications of TT are similar to conservative procedures. The recurrence of goiter and ITC require a second surgical procedure, with a higher risk of complications. So we can claim that the standard surgical treatment of bilateral PBT would be represented by TT.
6
421
427
Incidental thyroid carcinoma (ITC): a retrospective study in a series of 737 patients treated for benign disease / Gelmini, Roberta; Franzoni, Chiara; Pavesi, Erica; Cabry, Francesca; Saviano, Massimo. - In: ANNALI ITALIANI DI CHIRURGIA. - ISSN 0003-469X. - STAMPA. - 6:(2010), pp. 421-427.
Gelmini, Roberta; Franzoni, Chiara; Pavesi, Erica; Cabry, Francesca; Saviano, Massimo
File in questo prodotto:
File Dimensione Formato  
421-428.pdf

non disponibili

Tipologia: Post-print dell'autore (bozza post referaggio)
Dimensione 78.38 kB
Formato Adobe PDF
78.38 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/649419
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 25
  • ???jsp.display-item.citation.isi??? 26
social impact