The essential oil of fruits of Cuminum cyminum L. (Apiaceae), from India, was analyzed by GC and GC-MS, and its antifungal activity was tested on dermatophytes and phytopathogens, fungi, yeasts and some new Aspergilli. The most abundant components were cumin aldehyde, pinenes, and p-cymene, and a fraction of oxygenate compounds such as alcohol and epoxides. Because of the large amount of the highly volatilecomponents in the cumin extract, we used a modified recent technique to evaluate the antifungal activity only of the volatile parts at doses from 5 to 20 μL of pure essential oil. Antifungal testing showed that Cuminum cyminum is active in general on all fungi but in particular on the dermatophytes, where Trichophyton rubrum was the most inhibited fungus also at the lowest dose of 5 μL. Less sensitive to treatmentwere the phytopathogens.

Antifungal activity of essential oil from fruits of Indian Cuminum cyminum / Romagnoli, Carlo; Andreotti, Elisa; S., Maietti; Mares, R. M. a. h. e. n. d. r. a. D.. - In: PHARMACEUTICAL BIOLOGY. - ISSN 1388-0209. - STAMPA. - 48:7(2010), pp. 834-838. [10.3109/13880200903283715]

Antifungal activity of essential oil from fruits of Indian Cuminum cyminum

ROMAGNOLI, Carlo;ANDREOTTI, Elisa;
2010

Abstract

The essential oil of fruits of Cuminum cyminum L. (Apiaceae), from India, was analyzed by GC and GC-MS, and its antifungal activity was tested on dermatophytes and phytopathogens, fungi, yeasts and some new Aspergilli. The most abundant components were cumin aldehyde, pinenes, and p-cymene, and a fraction of oxygenate compounds such as alcohol and epoxides. Because of the large amount of the highly volatilecomponents in the cumin extract, we used a modified recent technique to evaluate the antifungal activity only of the volatile parts at doses from 5 to 20 μL of pure essential oil. Antifungal testing showed that Cuminum cyminum is active in general on all fungi but in particular on the dermatophytes, where Trichophyton rubrum was the most inhibited fungus also at the lowest dose of 5 μL. Less sensitive to treatmentwere the phytopathogens.
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7
834
838
Antifungal activity of essential oil from fruits of Indian Cuminum cyminum / Romagnoli, Carlo; Andreotti, Elisa; S., Maietti; Mares, R. M. a. h. e. n. d. r. a. D.. - In: PHARMACEUTICAL BIOLOGY. - ISSN 1388-0209. - STAMPA. - 48:7(2010), pp. 834-838. [10.3109/13880200903283715]
Romagnoli, Carlo; Andreotti, Elisa; S., Maietti; Mares, R. M. a. h. e. n. d. r. a. D.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/648911
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