A technique using indirect immunoperoxidase antibody was developed for the detection of specific serum IgA antibody to Epstein-Barr virus capsid antigen and early antigen. The IgA technique was compared with an immunofluorescence antibody method. Epstein-Barr virus IgA antibody against viral capsid antigen was detected in all nine patients with Epstein-Barr virus associated undifferentiated nasopharyngeal carcinoma, in 13 (72.2%) of 18 patients with infectious mononucleosis, in 21 (28.3%) of 74 patients with acute lymphoblastic leukaemia, and in six (20%) of 30 patients who had recently had kidney transplants. Epstein-Barr virus IgA antibody against viral capsid antigen was also detected in four (10%) of 40 healthy subjects, but it was not found in any of 20 cord blood samples. Epstein-Barr virus IgA antibody to early antigen was detected in six (66.6%) patients with nasopharyngeal carcinoma and in two (2.7%) patients with acute lymphoblastic leukaemia. The immunoperoxidase assay for Epstein-Barr virus specific IgA was simple, reliable, and rapid and correlated well (r = 0.94) with the immunofluorescence antibody technique.
|Data di pubblicazione:||1984|
|Titolo:||An immunoperoxidase assay for the detection of specific IgA antibody in Epstein-Barr virus infections.|
|Autore/i:||Cevenini, R; Donati, M; Rumpianesi, F; Moroni, A; PAOLUCCI, Paolo|
|Codice identificativo ISI:||WOS:A1984SL40800015|
|Codice identificativo Scopus:||2-s2.0-0021328112|
|Codice identificativo Pubmed:||6323549|
|Citazione:||An immunoperoxidase assay for the detection of specific IgA antibody in Epstein-Barr virus infections / Cevenini, R; Donati, M; Rumpianesi, F; Moroni, A; PAOLUCCI, Paolo. - In: JOURNAL OF CLINICAL PATHOLOGY. - ISSN 0021-9746. - STAMPA. - 37(4)(1984), pp. 440-443.|
|Tipologia||Articolo su rivista|
File in questo prodotto:
I documenti presenti in Iris Unimore sono rilasciati con licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 3.0 Italia, salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris