We report a case of Usutu virus (USUV)-related illness in a patient that underwent an orthotropic liver transplant (OLT). Post transplant, the patient developed clinical signs of a possible neuroinvasive disease with a significant loss of cerebral functions. USUV was isolated in Vero E6 cells from a plasma sample obtained immediately before the surgery, and USUV RNA was demonstrated by RT-PCR and sequencing. This report enlarges the panel of emerging mosquito-borne flavivirus-related disease in humans.
Usutu virus infection in a patient who underwent orthotropic liver transplantation, Italy, August-September 2009 / Cavrini, F; Gaibani, P; Longo, Fulvio Giovanni; Pierro, Am; Rossini, Gian Paolo; Bonilauri, P; Gerunda, Giorgio Enrico; DI BENEDETTO, Fabrizio; Pasetto, Alberto; Girardis, Massimo; Dottori, M; Landini, Mp; Sambri, V.. - In: EUROSURVEILLANCE. - ISSN 1560-7917. - STAMPA. - 14:50(2009), pp. 17-18.
Usutu virus infection in a patient who underwent orthotropic liver transplantation, Italy, August-September 2009.
LONGO, Fulvio Giovanni;ROSSINI, Gian Paolo;GERUNDA, Giorgio Enrico;DI BENEDETTO, Fabrizio;PASETTO, Alberto;GIRARDIS, Massimo;
2009
Abstract
We report a case of Usutu virus (USUV)-related illness in a patient that underwent an orthotropic liver transplant (OLT). Post transplant, the patient developed clinical signs of a possible neuroinvasive disease with a significant loss of cerebral functions. USUV was isolated in Vero E6 cells from a plasma sample obtained immediately before the surgery, and USUV RNA was demonstrated by RT-PCR and sequencing. This report enlarges the panel of emerging mosquito-borne flavivirus-related disease in humans.
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