Since their initial description, mesenchymal progenitors have exhibited two general functions: to directly generate tissue by differentiation and to support the survival and proliferation of other cells/tissues by secreting cytokines or growth factors. This dual-function paradigm was represented in the original description of mesenchymal progenitors, now designated as marrow stromal cells (MSC), by their capacity to give rise to bone cells and to support hematopoiesis in vitro.

Getting beneath the skin to understand MSC complexity / Dominici, Massimo; E. M., Horwitz. - In: CYTOTHERAPY. - ISSN 1465-3249. - STAMPA. - 12:4(2010), pp. 438-439. [10.3109/14653249.2010.499712]

Getting beneath the skin to understand MSC complexity

DOMINICI, Massimo;
2010

Abstract

Since their initial description, mesenchymal progenitors have exhibited two general functions: to directly generate tissue by differentiation and to support the survival and proliferation of other cells/tissues by secreting cytokines or growth factors. This dual-function paradigm was represented in the original description of mesenchymal progenitors, now designated as marrow stromal cells (MSC), by their capacity to give rise to bone cells and to support hematopoiesis in vitro.
2010
12
4
438
439
Getting beneath the skin to understand MSC complexity / Dominici, Massimo; E. M., Horwitz. - In: CYTOTHERAPY. - ISSN 1465-3249. - STAMPA. - 12:4(2010), pp. 438-439. [10.3109/14653249.2010.499712]
Dominici, Massimo; E. M., Horwitz
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/646519
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