We have carried out an in vitro study on the interactions of human macrophages (J111) with two different membranes made of collagen type I and II, isolated from horse tendon and from horse articular and trachea cartilagene in order to obtain data on their biocompatibility. We have described the morphology of cell seeded on collagen films, and we have evaluated their proliferation as well as cytokine production as indicator of macrophage activation. The inflammatory response may in fact induce the destruction of collagen membranes and may interfere with cell and tissue behaviour. Results might be relevant for in vivo application such ad “tissue engeneering” and /or specialized cells implantation.

BIOCOMPATIBILITY OF COLLAGEN MEMBRANES ASSESSED BY CULTURING HUMAN J111 MACROPHAGES CELLS / Aruta, CLAUDIA GAETANA; Croce, Maria Antonietta; Quaglino, Daniela; Guerra, Deanna; Tiozzo, Roberta. - In: MATERIALS. - ISSN 1996-1944. - ELETTRONICO. - 2:3(2009), pp. 945-957. [10.3390/ma2030945]

BIOCOMPATIBILITY OF COLLAGEN MEMBRANES ASSESSED BY CULTURING HUMAN J111 MACROPHAGES CELLS.

ARUTA, CLAUDIA GAETANA;CROCE, Maria Antonietta;QUAGLINO, Daniela;GUERRA, Deanna;TIOZZO, Roberta
2009

Abstract

We have carried out an in vitro study on the interactions of human macrophages (J111) with two different membranes made of collagen type I and II, isolated from horse tendon and from horse articular and trachea cartilagene in order to obtain data on their biocompatibility. We have described the morphology of cell seeded on collagen films, and we have evaluated their proliferation as well as cytokine production as indicator of macrophage activation. The inflammatory response may in fact induce the destruction of collagen membranes and may interfere with cell and tissue behaviour. Results might be relevant for in vivo application such ad “tissue engeneering” and /or specialized cells implantation.
2
3
945
957
BIOCOMPATIBILITY OF COLLAGEN MEMBRANES ASSESSED BY CULTURING HUMAN J111 MACROPHAGES CELLS / Aruta, CLAUDIA GAETANA; Croce, Maria Antonietta; Quaglino, Daniela; Guerra, Deanna; Tiozzo, Roberta. - In: MATERIALS. - ISSN 1996-1944. - ELETTRONICO. - 2:3(2009), pp. 945-957. [10.3390/ma2030945]
Aruta, CLAUDIA GAETANA; Croce, Maria Antonietta; Quaglino, Daniela; Guerra, Deanna; Tiozzo, Roberta
File in questo prodotto:
File Dimensione Formato  
materials-02-00945.pdf

accesso aperto

Tipologia: Versione dell'editore (versione pubblicata)
Dimensione 1.04 MB
Formato Adobe PDF
1.04 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/644492
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 4
  • ???jsp.display-item.citation.isi??? 3
social impact