Cardiovascular diseases (CVD) are responsible for significant morbidity and mortality throughout the world. We present a first investigation using HR-MAS NMR Spectroscopy in combination with GC/MS of neonatal rat cardiomyocytes supplemented with two different PUFAs, EPA and DHA, in order to understand the metabolic change occurring in these cells following the increase of their n-3 PUFA content. EPA and DHA are of special importance for human health, and fish oil feeding has beenassociated to reduced mortality in several studies.
Metabolic aspects of n-3 PUFAs supplementation to rat cardiomyocytes: a HR-MAS NMR and GC/MS study / Righi, V., M., D.N., F., D., E., B., Schenetti, L., Mucci, A., A., B., V., T.. - STAMPA. - 18:(2010), pp. 922-922. (ISMRM-ESMRMB 18th annual meeting Stoccolma, Svezia 1-7 maggio 2010).
Metabolic aspects of n-3 PUFAs supplementation to rat cardiomyocytes: a HR-MAS NMR and GC/MS study
RIGHI, VALERIA;SCHENETTI, Luisa;MUCCI, Adele;
2010
Abstract
Cardiovascular diseases (CVD) are responsible for significant morbidity and mortality throughout the world. We present a first investigation using HR-MAS NMR Spectroscopy in combination with GC/MS of neonatal rat cardiomyocytes supplemented with two different PUFAs, EPA and DHA, in order to understand the metabolic change occurring in these cells following the increase of their n-3 PUFA content. EPA and DHA are of special importance for human health, and fish oil feeding has beenassociated to reduced mortality in several studies.
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