Glass ceramic with a nominal composition of 35.6% CaO, 12.8% MgO and 51.6% SiO2 was prepared bytransferred arc plasma processing. The in vitro bioactivity of the plasma synthesized CaO–MgO–SiO2 glassceramic was examined for its biomedical applicability which was evaluated by immersion in simulated bodyfluid at 36.5 °C for several days. The apatite particles were found to be formed on the surface of the glassceramic and grew with the passage of soaking time. The simulated body fluid test results showed theformation of carbonated hydroxyapatite like layer on the surface of the glass ceramic. The cytocompatibilitywas evaluated through human fibroblast proliferation. The fibroblasts adhere, spread, and proliferate on theCaO–MgO–SiO2 glass ceramic, and the cell proliferation was more obvious.
Bioactivity of CaO–MgO–SiO2 glass ceramics synthesized using transferred arc plasma (TAP) process / C. P., Yoganand; V., Selvarajan; Lusvarghi, Luca; O. M., Goudouri; K. M., Paraskevopoulos; M., Rouabhia. - In: MATERIALS SCIENCE AND ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS. - ISSN 0928-4931. - STAMPA. - 29:5(2009), pp. 1759-1764. [10.1016/j.msec.2009.01.028]
Bioactivity of CaO–MgO–SiO2 glass ceramics synthesized using transferred arc plasma (TAP) process
LUSVARGHI, Luca;
2009
Abstract
Glass ceramic with a nominal composition of 35.6% CaO, 12.8% MgO and 51.6% SiO2 was prepared bytransferred arc plasma processing. The in vitro bioactivity of the plasma synthesized CaO–MgO–SiO2 glassceramic was examined for its biomedical applicability which was evaluated by immersion in simulated bodyfluid at 36.5 °C for several days. The apatite particles were found to be formed on the surface of the glassceramic and grew with the passage of soaking time. The simulated body fluid test results showed theformation of carbonated hydroxyapatite like layer on the surface of the glass ceramic. The cytocompatibilitywas evaluated through human fibroblast proliferation. The fibroblasts adhere, spread, and proliferate on theCaO–MgO–SiO2 glass ceramic, and the cell proliferation was more obvious.
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