A study on IgE - IgA plasmatic level has been carried out in the acute phase and in remission of minimal changes nephrosis (MCN) and in glomerulonephritis with nephrotic syndrome (NS). The results obtained are the following: (1) Mean values of Ig classes were impaired in comparison with the normal values of children of the same age, bon MCN and NS. (2) IgE were increased, particularly in children over 6 years in the MCN acute phase; the values decreased within normal after the remission was achieved. (3) IgA, on the contrary, were decreased in the subjects over 6 years, in the MCN acute phase. (4) No significant correlation was found between the two Ig classes. (5) The modification of the Ig plasmatic level during the remission, after corticosteroid therapy was characterized by IgE reduction; IgA were only slightly, but not significantly, decreased in the same phase.
Correlazione tra IGE e IGA plasmatiche nella nefrosi infantile e nella sindrome nefrosica / A., Guerra; T., Cappellini; C., Chiossi; G., Bonvini; Lalla, Michele; Genova, Rosalia. - In: PEDIATRIA MEDICA E CHIRURGICA. - ISSN 0391-5387. - STAMPA. - 4:(1982), pp. 425-434.
Correlazione tra IGE e IGA plasmatiche nella nefrosi infantile e nella sindrome nefrosica
LALLA, Michele;GENOVA, Rosalia
1982
Abstract
A study on IgE - IgA plasmatic level has been carried out in the acute phase and in remission of minimal changes nephrosis (MCN) and in glomerulonephritis with nephrotic syndrome (NS). The results obtained are the following: (1) Mean values of Ig classes were impaired in comparison with the normal values of children of the same age, bon MCN and NS. (2) IgE were increased, particularly in children over 6 years in the MCN acute phase; the values decreased within normal after the remission was achieved. (3) IgA, on the contrary, were decreased in the subjects over 6 years, in the MCN acute phase. (4) No significant correlation was found between the two Ig classes. (5) The modification of the Ig plasmatic level during the remission, after corticosteroid therapy was characterized by IgE reduction; IgA were only slightly, but not significantly, decreased in the same phase.
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