A key intermediate for the synthesis of Tyromycin A, a C-20 tetrachlorodicarboxylic acid, was produced in six steps starting with a dimerisation of methyl 10-undecenoate which was obtained from a renewable resource, e.g. castor oil. The acyloin condensation product was then oxidised, transformed to the diene, followed by ozonisation, chlorination and finally oxidation to the corresponding tetrachlorodicarboxylic acid.

Undecylenic acid: a valuable renewable Building Block on route to Tyromycin A derivatives / M., Van der Steen; C. V., Stevens; Y., Eeckhout; L., De Buyck; Ghelfi, Franco; Roncaglia, Fabrizio. - In: EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY. - ISSN 1438-9312. - STAMPA. - 110:(2008), pp. 846-852.

Undecylenic acid: a valuable renewable Building Block on route to Tyromycin A derivatives

GHELFI, Franco;RONCAGLIA, Fabrizio
2008

Abstract

A key intermediate for the synthesis of Tyromycin A, a C-20 tetrachlorodicarboxylic acid, was produced in six steps starting with a dimerisation of methyl 10-undecenoate which was obtained from a renewable resource, e.g. castor oil. The acyloin condensation product was then oxidised, transformed to the diene, followed by ozonisation, chlorination and finally oxidation to the corresponding tetrachlorodicarboxylic acid.
110
846
852
Undecylenic acid: a valuable renewable Building Block on route to Tyromycin A derivatives / M., Van der Steen; C. V., Stevens; Y., Eeckhout; L., De Buyck; Ghelfi, Franco; Roncaglia, Fabrizio. - In: EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY. - ISSN 1438-9312. - STAMPA. - 110:(2008), pp. 846-852.
M., Van der Steen; C. V., Stevens; Y., Eeckhout; L., De Buyck; Ghelfi, Franco; Roncaglia, Fabrizio
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/620358
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 20
  • ???jsp.display-item.citation.isi??? 21
social impact