Two series of glasses of general formula (2-p) SiO21.1Na2OCaOpP2O5xZnO (p = 0.10, 0.20; x = 0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chem. surface features before and after contact with simulated body fluid, morphol. characteristics, and osteoblast-like cells behavior when cultured on them. The resulted good cell adhesion and growth, along with nonsignificant changes of the focal contacts, allow the authors to indicate HZ5 and HP5Z5 glasses as the ones having optimal ratio of Zn/P to maintain acceptable cell behavior, comparable to the bioactive glass (Bioglass) used as a control; results are also rationalized by means of three-dimensional models derived by mol. dynamic simulations, with decompn. and conversion rates optimized with respect to the parent Hench's Bioglass.

Properties of zinc releasing surfaces for clinical applications / Lusvardi, Gigliola; Malavasi, Gianluca; Menabue, Ledi; Menziani, Maria Cristina; Pedone, Alfonso; Segre, Ulderico; Aina, V; Perardi, A; Morterra, C; Boccafoschi, F; Gatti, S; Bosetti, M; Cannas, M.. - In: JOURNAL OF BIOMATERIALS APPLICATIONS. - ISSN 0885-3282. - STAMPA. - 22:6(2008), pp. 505-526. [10.1177/0885328207079731]

Properties of zinc releasing surfaces for clinical applications

LUSVARDI, Gigliola;MALAVASI, Gianluca;MENABUE, Ledi;MENZIANI, Maria Cristina;PEDONE, Alfonso;SEGRE, Ulderico;
2008

Abstract

Two series of glasses of general formula (2-p) SiO21.1Na2OCaOpP2O5xZnO (p = 0.10, 0.20; x = 0.0, 0.16, 0.35, and 0.78) have been analyzed for physico-chem. surface features before and after contact with simulated body fluid, morphol. characteristics, and osteoblast-like cells behavior when cultured on them. The resulted good cell adhesion and growth, along with nonsignificant changes of the focal contacts, allow the authors to indicate HZ5 and HP5Z5 glasses as the ones having optimal ratio of Zn/P to maintain acceptable cell behavior, comparable to the bioactive glass (Bioglass) used as a control; results are also rationalized by means of three-dimensional models derived by mol. dynamic simulations, with decompn. and conversion rates optimized with respect to the parent Hench's Bioglass.
2008
22
6
505
526
Properties of zinc releasing surfaces for clinical applications / Lusvardi, Gigliola; Malavasi, Gianluca; Menabue, Ledi; Menziani, Maria Cristina; Pedone, Alfonso; Segre, Ulderico; Aina, V; Perardi, A; Morterra, C; Boccafoschi, F; Gatti, S; Bosetti, M; Cannas, M.. - In: JOURNAL OF BIOMATERIALS APPLICATIONS. - ISSN 0885-3282. - STAMPA. - 22:6(2008), pp. 505-526. [10.1177/0885328207079731]
Lusvardi, Gigliola; Malavasi, Gianluca; Menabue, Ledi; Menziani, Maria Cristina; Pedone, Alfonso; Segre, Ulderico; Aina, V; Perardi, A; Morterra, C; Boccafoschi, F; Gatti, S; Bosetti, M; Cannas, M.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/613404
Citazioni
  • ???jsp.display-item.citation.pmc??? 4
  • Scopus 54
  • ???jsp.display-item.citation.isi??? 53
social impact