BACKGROUND: Both psychological and organic factors have been recognized to be associated with sexual dysfunction in HIV-infected individuals. METHODS: In this cross-sectional study we evaluated the prevalence and factors associated with sexual dysfunction in a cohort of HIV-infected adult men. Evaluation tools included: the International Index of Erectile Function (erectile dysfunction [ED], desire, orgasm, intercourse satisfaction, overall satisfaction), the Assessment of Body Change and Distress (body image satisfaction), the Medical Outcomes Study HIV Health Survey (mental and physical health-related quality of life), and plasma free and total testosterone level (hypogonadism). RESULTS: Three-hundred and fifty-seven men were enrolled. Among 336 patients reporting sexual activities in the 4 weeks before, 94 (29.6%) had mild, 30 (9.4%) moderate and 34 (10.1%) severe dysfunction. The Mental Health Summary score was 2.28 units (95% confidence interval [CI] 1.51, 3.06) lower for each unit higher of body image dissatisfaction and 0.31 units (95% CI 0.27, 0.36) higher for each unit higher of the score for body change interference with habits. At regression analysis, ED was independently related to the body mass index (B = 0.31, 95% CI 0.08, 0.62). Desire, orgasm and overall satisfaction domains were associated with mental health score (B = 0.87, 95% CI 0.47, 1.27; B = 0.75, 95% CI 0.23, 1.26; B = 0.86, 95% CI 0.45, 1.28, respectively). An improved intercourse satisfaction domain was associated with a lower interference of body changes with habits and social life (B = 0.39, 95% CI 0.05, 0.73). Testosterone, metabolic alterations and HAART were not associated with sexual function domains. CONCLUSIONS: Body image and mental health but not HAART or hypogonadism were associated with sexual function domains.

Sexual dysfunction in HIV-infected men: role of antiretroviral therapy, hypogonadism and lipodystrophy / Guaraldi, Giovanni; Luzi, K.; Murri, R.; Granata, A.; De Paola, M.; Orlando, G.; Squillace, N.; Malmusi, D.; Carani, Cesare; Comelli, D.; Esposito, Roberto; Martinez, E.. - In: ANTIVIRAL THERAPY. - ISSN 1359-6535. - ELETTRONICO. - 12(7):(2007), pp. 1059-1065.

Sexual dysfunction in HIV-infected men: role of antiretroviral therapy, hypogonadism and lipodystrophy.

GUARALDI, Giovanni;CARANI, Cesare;ESPOSITO, Roberto;
2007

Abstract

BACKGROUND: Both psychological and organic factors have been recognized to be associated with sexual dysfunction in HIV-infected individuals. METHODS: In this cross-sectional study we evaluated the prevalence and factors associated with sexual dysfunction in a cohort of HIV-infected adult men. Evaluation tools included: the International Index of Erectile Function (erectile dysfunction [ED], desire, orgasm, intercourse satisfaction, overall satisfaction), the Assessment of Body Change and Distress (body image satisfaction), the Medical Outcomes Study HIV Health Survey (mental and physical health-related quality of life), and plasma free and total testosterone level (hypogonadism). RESULTS: Three-hundred and fifty-seven men were enrolled. Among 336 patients reporting sexual activities in the 4 weeks before, 94 (29.6%) had mild, 30 (9.4%) moderate and 34 (10.1%) severe dysfunction. The Mental Health Summary score was 2.28 units (95% confidence interval [CI] 1.51, 3.06) lower for each unit higher of body image dissatisfaction and 0.31 units (95% CI 0.27, 0.36) higher for each unit higher of the score for body change interference with habits. At regression analysis, ED was independently related to the body mass index (B = 0.31, 95% CI 0.08, 0.62). Desire, orgasm and overall satisfaction domains were associated with mental health score (B = 0.87, 95% CI 0.47, 1.27; B = 0.75, 95% CI 0.23, 1.26; B = 0.86, 95% CI 0.45, 1.28, respectively). An improved intercourse satisfaction domain was associated with a lower interference of body changes with habits and social life (B = 0.39, 95% CI 0.05, 0.73). Testosterone, metabolic alterations and HAART were not associated with sexual function domains. CONCLUSIONS: Body image and mental health but not HAART or hypogonadism were associated with sexual function domains.
12(7)
1059
1065
Sexual dysfunction in HIV-infected men: role of antiretroviral therapy, hypogonadism and lipodystrophy / Guaraldi, Giovanni; Luzi, K.; Murri, R.; Granata, A.; De Paola, M.; Orlando, G.; Squillace, N.; Malmusi, D.; Carani, Cesare; Comelli, D.; Esposito, Roberto; Martinez, E.. - In: ANTIVIRAL THERAPY. - ISSN 1359-6535. - ELETTRONICO. - 12(7):(2007), pp. 1059-1065.
Guaraldi, Giovanni; Luzi, K.; Murri, R.; Granata, A.; De Paola, M.; Orlando, G.; Squillace, N.; Malmusi, D.; Carani, Cesare; Comelli, D.; Esposito, Roberto; Martinez, E.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/613334
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