Cutaneous lesions are frequent in medium-sized and small vessel systemic vasculitides. The classic cutaneous manifestation of vasculitis is palpable purpura; however the clinical manifestations greatly depend on the size of the vessels affected. They usually do not affect prognosis but relapsing or intractable forms have been described. When skin manifestations are only one of the clinical signs of vasculitis. treatment with corticosteroids and, when indicated, an inununosuppressant, is mandatory, which usually leads to the rapid disappearance of cutaneous lesions. Conversely, when skin lesions are isolated, the diagnosis can be snore challenging, but initial treatment may be less aggressive, e.g., dapsone or colchicine, reserving corticosteroids only for those patients in whom the former are ineffective. Erythema nodosum (EN) is the most frequent septal panniculitis. In general it is characterized by the sudden eruption of one or more erythematous and tender nodules or plaques located mainly over the extensor sides of lower extremities. EN resolves with complete '' restitutio ad integrum '' of the skin in 3-6 weeks. Relapses are uncommon but inpatients with idiophatic, streptococcal or EN associated with other upper respiratory tract infections they are more frequent. The main treatment of EN is that of the underlying associated conditions, if demonstrated. Aspirin and other NSAIDs in full doses are often sufficient.

Skin manifestations in vasculitis and erythema nodosum / Atzeni, F; Carrabba, M; Davin, Jc; Frances, C; Ferri, Clodoveo; Guillevin, L; Jorizzo, Jl; Mascia, Maria Teresa; Patel, Mj; Pagnoux, C; Vulpio, L; Sarzi Puttini, P.. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - STAMPA. - 24:40(2006), pp. S60-S66.

Skin manifestations in vasculitis and erythema nodosum

FERRI, Clodoveo;MASCIA, Maria Teresa;
2006

Abstract

Cutaneous lesions are frequent in medium-sized and small vessel systemic vasculitides. The classic cutaneous manifestation of vasculitis is palpable purpura; however the clinical manifestations greatly depend on the size of the vessels affected. They usually do not affect prognosis but relapsing or intractable forms have been described. When skin manifestations are only one of the clinical signs of vasculitis. treatment with corticosteroids and, when indicated, an inununosuppressant, is mandatory, which usually leads to the rapid disappearance of cutaneous lesions. Conversely, when skin lesions are isolated, the diagnosis can be snore challenging, but initial treatment may be less aggressive, e.g., dapsone or colchicine, reserving corticosteroids only for those patients in whom the former are ineffective. Erythema nodosum (EN) is the most frequent septal panniculitis. In general it is characterized by the sudden eruption of one or more erythematous and tender nodules or plaques located mainly over the extensor sides of lower extremities. EN resolves with complete '' restitutio ad integrum '' of the skin in 3-6 weeks. Relapses are uncommon but inpatients with idiophatic, streptococcal or EN associated with other upper respiratory tract infections they are more frequent. The main treatment of EN is that of the underlying associated conditions, if demonstrated. Aspirin and other NSAIDs in full doses are often sufficient.
2006
24
40
S60
S66
Skin manifestations in vasculitis and erythema nodosum / Atzeni, F; Carrabba, M; Davin, Jc; Frances, C; Ferri, Clodoveo; Guillevin, L; Jorizzo, Jl; Mascia, Maria Teresa; Patel, Mj; Pagnoux, C; Vulpio, L; Sarzi Puttini, P.. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 0392-856X. - STAMPA. - 24:40(2006), pp. S60-S66.
Atzeni, F; Carrabba, M; Davin, Jc; Frances, C; Ferri, Clodoveo; Guillevin, L; Jorizzo, Jl; Mascia, Maria Teresa; Patel, Mj; Pagnoux, C; Vulpio, L; Sar...espandi
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/611870
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 14
  • ???jsp.display-item.citation.isi??? 10
social impact