The aim of this study was to assess the relationship between preterm/early preterm delivery and active smoking as well as environmental tobacco smoke (ETS) exposure in a sample of pregnant Italian women. A case-control study was conducted in nine cities in Italy between October 1999 and September 2000. Cases of preterm birth were singleton babies born before the 37th gestational week; babies born before the 35th gestational week were considered early preterm births. Controls were babies with gestational ages ≥ 37th week. A total of 299 preterm cases (including 105 early preterm) and 855 controls were analysed. A self-administered questionnaire was used to assess active smoking and ETS exposure, as well as potential confounders. Multivariable logistic regression analysis showed a relationship between active smoking during pregnancy and preterm/early preterm delivery [adjusted ORs: 1.53; 95% CI 1.05, 2.21 and 2.00; 95% CI 1.16, 3.45, respectively]. A dose-response relationship was found for the number of cigarettes smoked daily. The adjusted ORs were 1.54 and 1.69 for preterm babies and 1.90 and 2.46 for early preterm babies for 1-10 and >10 cigarettes/day respectively. ETS exposure was associated with early preterm delivery [adjusted OR 1.56; 95% CI 0.99, 2.46] with a dose-response relationship with the number of smokers in the home. Smoking during pregnancy was strongly associated with preterm delivery with a dose-response effect. ETS exposure in non-smoking women was associated only with early preterm delivery.

Preterm delivery and exposure to active and passive smoking during pregnancy: a case-control study from Italy / Fantuzzi, Guglielmina; Aggazzotti, Gabriella; Righi, Elena; Facchinetti, Fabio; Bertucci, Emma; S., Kanitz; F., Barbone; G., Sansebastiano; M. A., Battaglia; V., Leoni; L., Fabiani; M., Triassi; S., Sciacca. - In: PAEDIATRIC AND PERINATAL EPIDEMIOLOGY. - ISSN 0269-5022. - STAMPA. - 21:(2007), pp. 194-200. [10.1111/j.1365-3016.2007.00815.x]

Preterm delivery and exposure to active and passive smoking during pregnancy: a case-control study from Italy

FANTUZZI, Guglielmina;AGGAZZOTTI, Gabriella;RIGHI, Elena;FACCHINETTI, Fabio;BERTUCCI, Emma;
2007

Abstract

The aim of this study was to assess the relationship between preterm/early preterm delivery and active smoking as well as environmental tobacco smoke (ETS) exposure in a sample of pregnant Italian women. A case-control study was conducted in nine cities in Italy between October 1999 and September 2000. Cases of preterm birth were singleton babies born before the 37th gestational week; babies born before the 35th gestational week were considered early preterm births. Controls were babies with gestational ages ≥ 37th week. A total of 299 preterm cases (including 105 early preterm) and 855 controls were analysed. A self-administered questionnaire was used to assess active smoking and ETS exposure, as well as potential confounders. Multivariable logistic regression analysis showed a relationship between active smoking during pregnancy and preterm/early preterm delivery [adjusted ORs: 1.53; 95% CI 1.05, 2.21 and 2.00; 95% CI 1.16, 3.45, respectively]. A dose-response relationship was found for the number of cigarettes smoked daily. The adjusted ORs were 1.54 and 1.69 for preterm babies and 1.90 and 2.46 for early preterm babies for 1-10 and >10 cigarettes/day respectively. ETS exposure was associated with early preterm delivery [adjusted OR 1.56; 95% CI 0.99, 2.46] with a dose-response relationship with the number of smokers in the home. Smoking during pregnancy was strongly associated with preterm delivery with a dose-response effect. ETS exposure in non-smoking women was associated only with early preterm delivery.
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Preterm delivery and exposure to active and passive smoking during pregnancy: a case-control study from Italy / Fantuzzi, Guglielmina; Aggazzotti, Gabriella; Righi, Elena; Facchinetti, Fabio; Bertucci, Emma; S., Kanitz; F., Barbone; G., Sansebastiano; M. A., Battaglia; V., Leoni; L., Fabiani; M., Triassi; S., Sciacca. - In: PAEDIATRIC AND PERINATAL EPIDEMIOLOGY. - ISSN 0269-5022. - STAMPA. - 21:(2007), pp. 194-200. [10.1111/j.1365-3016.2007.00815.x]
Fantuzzi, Guglielmina; Aggazzotti, Gabriella; Righi, Elena; Facchinetti, Fabio; Bertucci, Emma; S., Kanitz; F., Barbone; G., Sansebastiano; M. A., Battaglia; V., Leoni; L., Fabiani; M., Triassi; S., Sciacca
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/611727
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