Persistent organic pollutants (POPs) can interfere with hormone activities and are suspected as endocrine disrupters involved in, e.g. reproductive disorders. We investigated the possible relation between the actual integrated serum xenoestrogenic, xenoandrogenic and aryl hydrocarbon receptor activities and the sperm DNA damage and sperm apoptotic markers of 262 adult males (54 Inuits from Greenland, 69 from Warsaw (Poland), 81 from Sweden and 58 from Kharkiv (Ukraine) exposed to different levels of POPs.
Relation between serum xenobiotic induced receptor activities and DNA damage and sperm apoptotic markers in European and Inuit populations / Long, M.; Stronati, A.; Bizzaro, D.; Kruger, T.; Manicardi, Gian Carlo; Hjelmborg, P. S.; Spano, M.; Giwercman, A.; Toft, G.; Bonde, J. P.; Bonefeld Jorgensen, E. C.. - In: TOXICOLOGY LETTERS. - ISSN 0378-4274. - STAMPA. - 180:(2008), pp. S189-S190. (Intervento presentato al convegno 45th Congress of the European-Societies-of-Toxicology tenutosi a Rhodes, GREECE nel OCT 05-08, 2008) [10.1016/j.toxlet.2008.06.193].
Relation between serum xenobiotic induced receptor activities and DNA damage and sperm apoptotic markers in European and Inuit populations
MANICARDI, Gian Carlo;
2008
Abstract
Persistent organic pollutants (POPs) can interfere with hormone activities and are suspected as endocrine disrupters involved in, e.g. reproductive disorders. We investigated the possible relation between the actual integrated serum xenoestrogenic, xenoandrogenic and aryl hydrocarbon receptor activities and the sperm DNA damage and sperm apoptotic markers of 262 adult males (54 Inuits from Greenland, 69 from Warsaw (Poland), 81 from Sweden and 58 from Kharkiv (Ukraine) exposed to different levels of POPs.
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