This collaborative study suggests that not only is the presence of a codon 12 glycine to valine mutation important for cancer progression but also that it predispose to more aggressive biological behaviour in patients with advanced colorectal cancer.

Kisten ras mutations in patients with colorectal cancer: the “RASCAL II” study / Andreyev, Hjn; Norman, Ar; Cunningham, D; Oates, J; Dix, Br; Iacopetta, Bj; Young, J; Walsh, T; Ward, R; Hawkins, N; Beranek, M; Jandik, P; Benamouzig, R; Jullian, E; LAURENT PUIG, P; Olschwang, S; Muller, O; Hoffmann, I; Rabes, Hm; Zietz, C; Troungos, C; Valavanis, C; Yuen, St; Ho, Jwc; Croke, Ct; Odonogue, Dp; Giaretti, W; Rapallo, A; Russo, A; Bazan, V; Tanaka, M; Omura, K; Onkusa, T; Fujimori, T; Ono, Y; Pauly, M; Faber, C; Glaesener, R; DE GOEIJ, Afpm; Arends, Jw; Andersen, Sn; Lovig, T; Breivik, J; Gaudernack, G; Clausen, Opf; DE ANGELIS, P; Meling, Gi; Rognum, To; Smith, R; Goh, H. S.; Font, A; Rosell, R; Sun, Xf; Zhang, H; Benhattar, J; Losi, Lorena; Lee, Jq; Wang, St; Clarke, Pa; Bell, S; Quirke, P; Bubb, Vj; Piris, J; Cruickshank, Nr; Morton, D; Fox, Jc; AL MULLA, F; Lees, N; Hall, Cn; Snary, D; Wilkinson, K; Dillon, D; Costa, J; Pricolo, Ve; Filkenstein, Sd; Thebo, Js; Senagore, Aj; Halter, Sa; Wadler, S; Malik, S; Krtolica, K; Urosevic, N.. - In: BRITISH JOURNAL OF CANCER. - ISSN 0007-0920. - STAMPA. - 85:(2001), pp. 692-696. [10.1054/bjoc.2001.1964]

Kisten ras mutations in patients with colorectal cancer: the “RASCAL II” study.

LOSI, Lorena;
2001

Abstract

This collaborative study suggests that not only is the presence of a codon 12 glycine to valine mutation important for cancer progression but also that it predispose to more aggressive biological behaviour in patients with advanced colorectal cancer.
2001
85
692
696
WOS:000171069800012
2-s2.0-0035444798
11531254
Kisten ras mutations in patients with colorectal cancer: the “RASCAL II” study / Andreyev, Hjn; Norman, Ar; Cunningham, D; Oates, J; Dix, Br; Iacopetta, Bj; Young, J; Walsh, T; Ward, R; Hawkins, N; Beranek, M; Jandik, P; Benamouzig, R; Jullian, E; LAURENT PUIG, P; Olschwang, S; Muller, O; Hoffmann, I; Rabes, Hm; Zietz, C; Troungos, C; Valavanis, C; Yuen, St; Ho, Jwc; Croke, Ct; Odonogue, Dp; Giaretti, W; Rapallo, A; Russo, A; Bazan, V; Tanaka, M; Omura, K; Onkusa, T; Fujimori, T; Ono, Y; Pauly, M; Faber, C; Glaesener, R; DE GOEIJ, Afpm; Arends, Jw; Andersen, Sn; Lovig, T; Breivik, J; Gaudernack, G; Clausen, Opf; DE ANGELIS, P; Meling, Gi; Rognum, To; Smith, R; Goh, H. S.; Font, A; Rosell, R; Sun, Xf; Zhang, H; Benhattar, J; Losi, Lorena; Lee, Jq; Wang, St; Clarke, Pa; Bell, S; Quirke, P; Bubb, Vj; Piris, J; Cruickshank, Nr; Morton, D; Fox, Jc; AL MULLA, F; Lees, N; Hall, Cn; Snary, D; Wilkinson, K; Dillon, D; Costa, J; Pricolo, Ve; Filkenstein, Sd; Thebo, Js; Senagore, Aj; Halter, Sa; Wadler, S; Malik, S; Krtolica, K; Urosevic, N.. - In: BRITISH JOURNAL OF CANCER. - ISSN 0007-0920. - STAMPA. - 85:(2001), pp. 692-696. [10.1054/bjoc.2001.1964]
Andreyev, Hjn; Norman, Ar; Cunningham, D; Oates, J; Dix, Br; Iacopetta, Bj; Young, J; Walsh, T; Ward, R; Hawkins, N; Beranek, M; Jandik, P; Benamouzig, R; Jullian, E; LAURENT PUIG, P; Olschwang, S; Muller, O; Hoffmann, I; Rabes, Hm; Zietz, C; Troungos, C; Valavanis, C; Yuen, St; Ho, Jwc; Croke, Ct; Odonogue, Dp; Giaretti, W; Rapallo, A; Russo, A; Bazan, V; Tanaka, M; Omura, K; Onkusa, T; Fujimori, T; Ono, Y; Pauly, M; Faber, C; Glaesener, R; DE GOEIJ, Afpm; Arends, Jw; Andersen, Sn; Lovig, T; Breivik, J; Gaudernack, G; Clausen, Opf; DE ANGELIS, P; Meling, Gi; Rognum, To; Smith, R; Goh, H. S.; Font, A; Rosell, R; Sun, Xf; Zhang, H; Benhattar, J; Losi, Lorena; Lee, Jq; Wang, St; Clarke, Pa; Bell, S; Quirke, P; Bubb, Vj; Piris, J; Cruickshank, Nr; Morton, D; Fox, Jc; AL MULLA, F; Lees, N; Hall, Cn; Snary, D; Wilkinson, K; Dillon, D; Costa, J; Pricolo, Ve; Filkenstein, Sd; Thebo, Js; Senagore, Aj; Halter, Sa; Wadler, S; Malik, S; Krtolica, K; Urosevic, N.
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