EnglishSince plasma reduced glutathione (GSH) seems to reflect liver GSH content, we have assessed plasma GSH in patients using paracetamol daily. In these patients a significant lower plasma GSH concentration was found with respect to controls. After the i.v. administration of GSH free plasma cysteine was 12 fold higher than in basal condition and all the pattern of plasma thiol groups was modified. This work suggests that the possible protective effect of GSH administration is due to the availability of plasma thiol compounds that enter the cell rather than GSH itself.
| Anno di pubblicazione: | 1992 |
| Titolo: | Plasma glutathione level in paracetamol daily abuser patients. Changes in plasma cysteine and thiol groups after reduced glutathione administration |
| Autori: | TRENTI T; BERTOLOTTI M; CASTELLANA CN; A. FERRARI; PINI LA; STERNIERI E |
| Autori: | |
| Rivista: | |
| Volume: | 64/65 |
| Pagina iniziale: | 757 |
| Pagina finale: | 761 |
| Appare nelle tipologie: | Articolo su rivista |
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti presenti in Iris Unimore sono rilasciati con licenza Creative Commons Attribuzione - Non commerciale - Non opere derivate 3.0 Italia, salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
Copyright © 2018