The transmission of a deleted in azoospermia (DAZ) deletion from a severely oligozoospermic patient to his son following intracytoplasmic sperm injection (ICSI) treatment is reported. The case report highlights the fertilizing capacity of spermatozoa carrying Y chromosome deletions in patients treated with ICSI and stresses the importance of genetic counselling in severe male infertility.
Transmission of a Y-chromosomal deletion involving DAZ and CDY genes from father to son through ICSI / Kamischke, A; Gromoll, J; Simoni, Manuela; Behre, Hm; Nieschlag, E.. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - ELETTRONICO. - 14:(1999), pp. 2320-2322.
Transmission of a Y-chromosomal deletion involving DAZ and CDY genes from father to son through ICSI.
SIMONI, Manuela;
1999
Abstract
The transmission of a deleted in azoospermia (DAZ) deletion from a severely oligozoospermic patient to his son following intracytoplasmic sperm injection (ICSI) treatment is reported. The case report highlights the fertilizing capacity of spermatozoa carrying Y chromosome deletions in patients treated with ICSI and stresses the importance of genetic counselling in severe male infertility.
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