SSAT modulation by putative regulators of folate cycle enzymes expression in cisplatin-sensitive and –resistant human ovarian cancer cell lines.Cisplatin (DDP)-resistance confers a deficient expression of spermidine/ spermine N(1)-acetyltransferase (SSAT) gene in response to the spermine analog N(1),N(12)-bis(ethyl)spermine (BESpm) in the DDP-resistant human ovarian carcinoma cell line (C13*), compared with their parental DDP-sensitive 2008 cells.
SSAT modulation by putative regulators of folate cycle enzymes expression in cisplatin-sensitive and –resistant human ovarian cancer cell lines / Marverti, G.; Ligabue, A.; Costi, M. P.; Lombardi, P.; Guerrieri, D.; Frassineti, C.; Monti, M. G.; Moruzzi, M. S.. - (2008), p. 24. (Intervento presentato al convegno Società di Biochimica Italiana tenutosi a Alberè di Tenna (Trento, Italy) nel May 14-18).
SSAT modulation by putative regulators of folate cycle enzymes expression in cisplatin-sensitive and –resistant human ovarian cancer cell lines.
G. MARVERTI;A. LIGABUE;M. P. COSTI;D. GUERRIERI;C. FRASSINETI;M. G. MONTI;M. S. MORUZZI
2008
Abstract
SSAT modulation by putative regulators of folate cycle enzymes expression in cisplatin-sensitive and –resistant human ovarian cancer cell lines.Cisplatin (DDP)-resistance confers a deficient expression of spermidine/ spermine N(1)-acetyltransferase (SSAT) gene in response to the spermine analog N(1),N(12)-bis(ethyl)spermine (BESpm) in the DDP-resistant human ovarian carcinoma cell line (C13*), compared with their parental DDP-sensitive 2008 cells.
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