Whether or not ELF-MF has genotoxic potential is a controversial issue. In the present study, we investigated the genotoxic effect using cytogenetic assays (CA - SCE - MN), in 109 workers exposed to ELF-MF. The mean value of occupational exposure in the whole group was 0.35 microT. According to the exposure level the workers were stratified in two different groups: low exposed (n. 39, TWA < or = 0.2 microT) and higher exposed (n. 70; TWA > 0.2 microT): the groups did not significantly differ for the examined variables. Due to these results we decided to re-evaluate the effect only considering the highest exposed workers: we selected 31 workers exposed to TWA levels exceeding 1 microT, and compared vs. the low exposed subjects: again, the difference in the groups examined were not significant. At multivariate regression analysis was also applied: no correlation was observed with cytogenetic biomarkers. The results of this study does not support the hypothesis of any direct genotoxic effect of ELF-MF, at least at the environmental levels currently found in an occupational settings.

Valutazione della genotossicità dei Campi Magnetici a Frequenza Estremamente Bassa (ELF- MF) in lavoratori esposti per ragioni professionali [Evaluation of the genotoxicity of the extremely low frequency-magnetic fields (ELF-MF) in workers exposed for professional reasons] / Scaringi, Meri; Temperani, Paola; Bravo, Giulia; Gobba, Fabriziomaria; Rossi, P. - In: GIORNALE ITALIANO DI MEDICINA DEL LAVORO ED ERGONOMIA. - ISSN 1592-7830. - STAMPA. - 29:3(2007), pp. 420-421. ((Intervento presentato al convegno 70° CONGRESSO NAZIONALE SIMLII tenutosi a ROMA nel 12-15 DICEMBRE 2007.

Valutazione della genotossicità dei Campi Magnetici a Frequenza Estremamente Bassa (ELF- MF) in lavoratori esposti per ragioni professionali [Evaluation of the genotoxicity of the extremely low frequency-magnetic fields (ELF-MF) in workers exposed for professional reasons]

SCARINGI, Meri;TEMPERANI, Paola;BRAVO, Giulia;GOBBA, Fabriziomaria;
2007

Abstract

Whether or not ELF-MF has genotoxic potential is a controversial issue. In the present study, we investigated the genotoxic effect using cytogenetic assays (CA - SCE - MN), in 109 workers exposed to ELF-MF. The mean value of occupational exposure in the whole group was 0.35 microT. According to the exposure level the workers were stratified in two different groups: low exposed (n. 39, TWA < or = 0.2 microT) and higher exposed (n. 70; TWA > 0.2 microT): the groups did not significantly differ for the examined variables. Due to these results we decided to re-evaluate the effect only considering the highest exposed workers: we selected 31 workers exposed to TWA levels exceeding 1 microT, and compared vs. the low exposed subjects: again, the difference in the groups examined were not significant. At multivariate regression analysis was also applied: no correlation was observed with cytogenetic biomarkers. The results of this study does not support the hypothesis of any direct genotoxic effect of ELF-MF, at least at the environmental levels currently found in an occupational settings.
70° CONGRESSO NAZIONALE SIMLII
ROMA
12-15 DICEMBRE 2007
29
420
421
Scaringi, Meri; Temperani, Paola; Bravo, Giulia; Gobba, Fabriziomaria; Rossi, P
Valutazione della genotossicità dei Campi Magnetici a Frequenza Estremamente Bassa (ELF- MF) in lavoratori esposti per ragioni professionali [Evaluation of the genotoxicity of the extremely low frequency-magnetic fields (ELF-MF) in workers exposed for professional reasons] / Scaringi, Meri; Temperani, Paola; Bravo, Giulia; Gobba, Fabriziomaria; Rossi, P. - In: GIORNALE ITALIANO DI MEDICINA DEL LAVORO ED ERGONOMIA. - ISSN 1592-7830. - STAMPA. - 29:3(2007), pp. 420-421. ((Intervento presentato al convegno 70° CONGRESSO NAZIONALE SIMLII tenutosi a ROMA nel 12-15 DICEMBRE 2007.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/597114
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