the model aims to fill one of the limitations possible limitations of the RBN model, that is the absence of the timing of the molecular processes at the basis of the mechanism of gene regulation. In real cells, proteins need time to be synthesized indeed and every protein is characterized by a specific decay time. In the classical RBN model the synthesis and the decay of proteins is considered to be instantaneous and is implicit in the links among the genes, which update synchronously in discrete time steps. In the model we are introducing, the link among every gene and its protein is made explicit and every single protein is characterized by specific synthesis and decay times, which will be fundamental in the dynamics.
A NEW MODEL OF GENETIC NETWORKS: THE GENE-PROTEIN NETWORK / Graudenzi, Alex; Serra, Roberto. - ELETTRONICO. - (2008), pp. 16-25. (Intervento presentato al convegno WIVACE 08 tenutosi a VENEZIA nel 8-10 SETTEMBRE 2008).
A NEW MODEL OF GENETIC NETWORKS: THE GENE-PROTEIN NETWORK
GRAUDENZI, Alex;SERRA, Roberto
2008
Abstract
the model aims to fill one of the limitations possible limitations of the RBN model, that is the absence of the timing of the molecular processes at the basis of the mechanism of gene regulation. In real cells, proteins need time to be synthesized indeed and every protein is characterized by a specific decay time. In the classical RBN model the synthesis and the decay of proteins is considered to be instantaneous and is implicit in the links among the genes, which update synchronously in discrete time steps. In the model we are introducing, the link among every gene and its protein is made explicit and every single protein is characterized by specific synthesis and decay times, which will be fundamental in the dynamics.Pubblicazioni consigliate
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