Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder of the lung characterized by poorly reversible airflow limitation. It is not a unique disease entity but rather a complex of conditions which include emphysema, chronic bronchitis and, sometimes, asthma. Moreover, COPD is a progressive disease often associated with exacerbations. Cigarette smoking, which is the most important risk factor for the development of COPD, induces pathological changes involving lung parenchyma, peripheral airways and central airways. Since lung parenchyma and peripheral airways are the sites responsible for airflow limitation and central airways are the main site of mucus hypersecretion, pathological changes in these compartments may be relevant in the development of COPD.

[Pathology of chronic obstructive pulmonary disease] / G., Turato; R., Zuin; S., Baraldo; C., Badin; Beghe', Bianca; M., Saetta. - In: ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ. - ISSN 0021-2571. - STAMPA. - 39:4(2003), pp. 507-517.

[Pathology of chronic obstructive pulmonary disease]

BEGHE', Bianca;
2003

Abstract

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder of the lung characterized by poorly reversible airflow limitation. It is not a unique disease entity but rather a complex of conditions which include emphysema, chronic bronchitis and, sometimes, asthma. Moreover, COPD is a progressive disease often associated with exacerbations. Cigarette smoking, which is the most important risk factor for the development of COPD, induces pathological changes involving lung parenchyma, peripheral airways and central airways. Since lung parenchyma and peripheral airways are the sites responsible for airflow limitation and central airways are the main site of mucus hypersecretion, pathological changes in these compartments may be relevant in the development of COPD.
2003
39
4
507
517
[Pathology of chronic obstructive pulmonary disease] / G., Turato; R., Zuin; S., Baraldo; C., Badin; Beghe', Bianca; M., Saetta. - In: ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ. - ISSN 0021-2571. - STAMPA. - 39:4(2003), pp. 507-517.
G., Turato; R., Zuin; S., Baraldo; C., Badin; Beghe', Bianca; M., Saetta
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/596447
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