Municipal waste incineration induces environmental contamination with toxic substances such as dioxins,furans and heavy metals, which have a teratogenic potential, but little epidemiologic evidence is available onthis topic. We examined the risk of congenital anomalies associated with maternal exposure to emissions of amodern municipal solid waste incinerator in a northern Italy community (Reggio Emilia, population about150,000) during the period 1998-2006 , through a population-based case-control study. In the analysis weincluded the livebirths and stillbirths as well as the induced abortions with diagnosis of congenital anomalies,and a corresponding series of control births, using maternal age as an additional matching variable and limitingthe analysis to women residing in the municipality. Sources of data were the Hospital Discharge Registry andthe population-based Registry of Birth Defects ‘IMER’ of the Emilia-Romagna Region, yielding an overallnumber of 352 congenital anomalies diagnoses and 352 control births during the study period. We calculatedthe risk of prevalence of birth defects in the offspring associated with maternal residence near the incinerator byusing a conditional logistic regression model. In the two periods (1998-2002 and 2006) of normal operation ofthe incinerator, among women residing <1 km and 1-2 km from the plant the prevalence of birth defects in theoffspring was not higher than that observed in the remaining municipal population. Furthermore, there was noreduction in the risk of congenital anomalies in the offspring of women residing up to 2 km from the incineratorin the shut-down period, from 2003 to 2005. Further adjustment for educational attainment level did notappreciably change these results. Findings of the study do not appear to support the hypothesis that theenvironmental contamination occurring around an incineration plant as examined in this study inducesteratogenic effects in the exposed population.
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|Data di pubblicazione:||2008|
|Titolo:||Prevalence of birth defects in a population living nearby a municipal solid waste incinerator with intermittent operativity.|
|Autori:||Vinceti M; Malagoli C; Teggi S; Fabbi S; Rodolfi R; Garavelli L; Astolfi G; Calzolari E.|
|Nome del convegno:||ISEE - International Society for Environmental Epidemiology 19th Annual Conference|
|Luogo del convegno:||Pasadena, California, USA|
|Data del convegno:||October 12-16, 2008|
|Appare nelle tipologie:||Abstract in Rivista|
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